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The impact of osteoarthritis on early exit from work: results from a population-based study

2018-04-11Journal article Open access
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dc.contributor.authorLaires, Pedro A.
dc.contributor.authorCanhão, Helena
dc.contributor.authorRodrigues, Ana M.
dc.contributor.authorEusébio, Mónica
dc.contributor.authorGouveia, Miguel
dc.contributor.authorBranco, Jaime C.
dc.date.accessioned2021-04-16T13:00:09Z
dc.date.available2021-04-16T13:00:09Z
dc.date.issued2018-04-11
dc.description.abstractBackground: Osteoarthritis (OA) is a leading cause of pain and disability, which may be a source of productivity losses. The objectives of this study were to describe the impact of OA, namely through pain and physical disability, on early exit from work and to calculate its economic burden. Methods: We analysed data from the national, cross-sectional, population-based EpiReumaPt study (Sep2011-Dec2013) in which 10,661 individuals were randomly surveyed in order to capture all cases of rheumatic diseases. We used all participants aged 50-64, near the official retirement age, who were clinically validated by experienced rheumatologists (n = 1286), including OA cases. A national database was used to calculate productivity values by gender, age and region, using the human capital approach. The impact of OA on the likelihood of early exit from work and the population attributable fractions used to calculate due economic burden (indirect costs) were obtained at the individual level by logistic regression. All results were based on weighted data. Results: Almost one third of the Portuguese population aged 50-64 had OA (29.7%; men: 16.2% and women: 43.5%) and more than half were out of paid work (51.8%). Only knee OA is associated with early exit from work (OR: 2.25; 95%CI: 1.42-3.59; p = 0.001), whereas other OA locations did not reach any statistical difference. Furthermore, we observed an association between self-reported longstanding musculoskeletal pain (OR: 1.55; 95%CI: 1.07-2.23; p = 0.02) and pain interference (OR: 1.35; 95%CI: 1.13-1.62; p = 0.001) with early exit from work. We also detected a clear relationship between levels of disability, measured by the Health Assessment Questionnaire (HAQ), and the probability of work withdrawal. The estimated annual cost of early exit from work attributable to OA was €656 million (€384 per capita; €1294 per OA patient and €2095 per OA patient out-of-work). Conclusions: In this study, we observed an association between OA and early exit from work, largely dependent on pain and disability. This relationship translates into a meaningful economic burden amounting to approximately 0.4% of the national Gross Domestic Product (GDP). The high prevalence and the impact of this disabling chronic disease highlight the need to prioritize policies targeting early exit from work in OA.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1186/s12889-018-5381-1pt_PT
dc.identifier.eid85045214514
dc.identifier.issn1471-2458
dc.identifier.pmid29642918
dc.identifier.urihttp://hdl.handle.net/10400.14/32665
dc.identifier.wos000429852800001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCost of illnesspt_PT
dc.subjectEarly retirementpt_PT
dc.subjectEconomic impactpt_PT
dc.subjectExit from workpt_PT
dc.subjectHealth surveypt_PT
dc.subjectIndirect costspt_PT
dc.subjectOsteoarthritispt_PT
dc.subjectWork disabilitypt_PT
dc.titleThe impact of osteoarthritis on early exit from work: results from a population-based studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.titleBMC Public Healthpt_PT
oaire.citation.volume18pt_PT
person.familyNameLaires
person.familyNameCanhão
person.familyNameRodrigues
person.familyNameGouveia
person.familyNameBranco
person.givenNamePedro
person.givenNameHelena
person.givenNameAna Maria
person.givenNameMiguel
person.givenNameJaime
person.identifier379800
person.identifier405554
person.identifier.ciencia-idB415-C750-5AAD
person.identifier.ciencia-id5A17-C6D9-DBC8
person.identifier.ciencia-idAE18-DA10-460C
person.identifier.ciencia-idDE17-C7DF-A591
person.identifier.ciencia-idB612-E5C3-60DC
person.identifier.orcid0000-0002-1930-7913
person.identifier.orcid0000-0003-1894-4870
person.identifier.orcid0000-0003-2046-8017
person.identifier.orcid0000-0003-0081-0508
person.identifier.orcid0000-0001-7024-4375
person.identifier.ridC-9611-2018
person.identifier.ridQ-2095-2015
person.identifier.scopus-author-id6602393492
person.identifier.scopus-author-id57189499663
person.identifier.scopus-author-id7003491970
person.identifier.scopus-author-id8417815400
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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