Publication
Phenethyl isothiocyanate, a bioactive agent for gastrointestinal health
| dc.contributor.author | Coscueta, Ezequiel | |
| dc.contributor.author | Sousa, Ana Sofia | |
| dc.contributor.author | Reis, Celso | |
| dc.contributor.author | Pintado, Manuela | |
| dc.date.accessioned | 2021-09-29T10:44:45Z | |
| dc.date.available | 2021-09-29T10:44:45Z | |
| dc.date.issued | 2021-02-25 | |
| dc.description.abstract | The incidence of gastrointestinal diseases (cancer in particular) has increased progressively with considerable morbidity, mortality, and a high economic impact on the healthcare system. Dietary intake of natural bioactive phytochemicals showed to have cancer-preventing and therapeutic effects. This includes the cruciferous vegetable derivative phenethyl isothiocyanate (PEITC), a bioactive compound from watercress. PEITC antioxidant, anti-inflammatory and anti-cancer properties are of particular importance. This review summarizes the current knowledge on the role of PEITC as a potential natural nutraceutical or an adjuvant against oxidative/inflammatory-related disorders in the gastrointestinal tract. We also discuss the safe and recommended dose of PEITC. Besides, we establish a framework to guide the research and development of sustainable methodologies for obtaining and stabilizing this natural nutraceutical for industrial use. This is a topic that still needs more scientific development, but with the potential to lead to a viable strategy in the prevention of cancer and other associated diseases of the gastrointestinal tract. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.20944/preprints202102.0592.v1 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.14/35301 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | no | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Gastrointestinal diseases | pt_PT |
| dc.subject | Natural anti-inflammatory | pt_PT |
| dc.subject | Natural antioxidant | pt_PT |
| dc.subject | Nutraceutical | pt_PT |
| dc.subject | Watercress | pt_PT |
| dc.title | Phenethyl isothiocyanate, a bioactive agent for gastrointestinal health | pt_PT |
| dc.type | preprint | |
| dspace.entity.type | Publication | |
| person.familyName | Coscueta | |
| person.familyName | Reis | |
| person.familyName | Pintado | |
| person.givenName | Ezequiel | |
| person.givenName | Celso | |
| person.givenName | Maria Manuela | |
| person.identifier | 456608 | |
| person.identifier.ciencia-id | 6614-705D-EBA7 | |
| person.identifier.ciencia-id | 2F13-AAE0-3405 | |
| person.identifier.orcid | 0000-0003-4496-2001 | |
| person.identifier.orcid | 0000-0002-0286-6639 | |
| person.identifier.orcid | 0000-0002-0760-3184 | |
| person.identifier.rid | J-7033-2016 | |
| person.identifier.rid | B-9969-2008 | |
| person.identifier.rid | F-5696-2013 | |
| person.identifier.scopus-author-id | 56986455000 | |
| person.identifier.scopus-author-id | 7103111131 | |
| person.identifier.scopus-author-id | 7004483898 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | preprint | pt_PT |
| relation.isAuthorOfPublication | f1f94059-86c8-4386-875f-a864386d54b4 | |
| relation.isAuthorOfPublication | d6e69fb7-425e-4545-b604-4e323419f7d6 | |
| relation.isAuthorOfPublication | ba387c7d-27c9-4016-895c-b35597e91ebc | |
| relation.isAuthorOfPublication.latestForDiscovery | ba387c7d-27c9-4016-895c-b35597e91ebc |
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