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Lipids obtained through fermentative processes have emerged as an excellent alternative to produce high-value molecules without compromising natural resources and meeting sustainable requirements [1]. A good example is squalene, the precursor of cholesterol in humans, known by protecting skin against UV radiation. It has been recently shown to reduce side-effects of chemotherapy and is widely used as adjuvant for pharmaceutical applications [2,3]. However, squalene is an unsaturated lipid and therefore susceptible to undergo oxidation. As a more stable alternative, processes to produce commercial squalane (SQ) and hemisqualane (HSQ) have been also developed.