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Bioactivity and bioaccessibility of bioactive compounds in gastrointestinal digestion of tomato bagasse extracts

dc.contributor.authorCoelho, Marta
dc.contributor.authorOliveira, Carla
dc.contributor.authorCoscueta, Ezequiel R.
dc.contributor.authorFernandes, João
dc.contributor.authorPereira, Ricardo N.
dc.contributor.authorTeixeira, José A.
dc.contributor.authorRodrigues, António Sebastião
dc.contributor.authorPintado, Manuela E.
dc.date.accessioned2022-04-22T16:24:59Z
dc.date.available2022-04-22T16:24:59Z
dc.date.issued2022-04-06
dc.description.abstractA nutrient-rich diet is a key to improving the chemical signals, such as antioxidants, which modulate pathogens’ resistance in the gut and prevent diseases. A current industrial problem is the generation of undervalued by-products, such as tomato bagasse, which are rich in bioactive compounds and of commercial interest (carotenoids and phenolic compounds). This work analyzed the effect of gastrointestinal digestion on the bioactivity and bioaccessibility of carotenoids and phenolic compounds from tomato bagasse extracts. Thus, the extraction by ohmic heating (OH) technology was compared with conventional (organic solvents). The results showed that the main phenolic compounds identified by UPLC-qTOF-MS were p-coumaric acid, naringenin, and luteolin. A higher recovery index for total phenolic compounds throughout the gastrointestinal digestion was observed for OH while for carotenoids, a strong reduction after stomach conditions was observed for both extracts. Furthermore, colon-available fraction exhibited a prebiotic effect upon different Bifidobacterium and Lactobacillus, but a strain-dependent and more accentuated effect on OH. Thus, the extraction technology highly influenced bioaccessibility, with OH demonstrating a positive impact on the recovery of bioactive compounds and related health benefits, such as antioxidant, anti-hypertensive, prebiotic, and anti-inflammatory properties. Of these properties, the last is demonstrated here for the first time.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/foods11071064pt_PT
dc.identifier.eid85128621113
dc.identifier.issn2304-8158
dc.identifier.pmcPMC8997470
dc.identifier.pmid35407151
dc.identifier.urihttp://hdl.handle.net/10400.14/37355
dc.identifier.wos000781055600001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCarotenoidspt_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectLycopersicon esculentumpt_PT
dc.subjectOhmic heatingpt_PT
dc.subjectBioaccessibilitypt_PT
dc.subjectBioactivitypt_PT
dc.titleBioactivity and bioaccessibility of bioactive compounds in gastrointestinal digestion of tomato bagasse extractspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFoodspt_PT
oaire.citation.volume11pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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