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Biodegradation of chiral pharmaceuticals by an activated sludge consortium followed by a Chiral HPLC-FD

2012-03Conference object Unknown
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dc.contributor.authorRibeiro, Ana R.
dc.contributor.authorCastro, P. M. L.
dc.contributor.authorAfonso, Carlos
dc.contributor.authorTiritan, Maria
dc.date.accessioned2013-11-14T15:40:31Z
dc.date.available2013-11-14T15:40:31Z
dc.date.issued2012-03
dc.description.abstractBiodegradation tends to be enantioselective in contrast to abiotic degradation and it is necessary enantioselective analytical methods to quantify the enantiomeric fraction of chiral pharmaceuticals in the environment for correct risk assessment. In this work, we developed HPLC-FD methods to follow the biodegradation of four beta-blockers: alprenolol , propranolol , metoprolol and atenolol and the antidepressant fluoxetine during 15 days in batch mode. The biodegradation assays were performed using AS from the aerated tanks of a municipal wastewater treatment plant with a singly compound supplementation and a mixture compound supplementation similar to those found in wastewater influents. Abiotic degradation in the presence of light and in the dark was evaluated. Either the low concentration or the mixture effects are situations closer to those found in the environment. The results indicate the higher degradation extents for the S-enantiomer forms, as is shown in Figure 1.por
dc.identifier.citationRIBEIRO, Ana R. [et al.] - Biodegradation of chiral pharmaceuticals by an activated sludge consortium followed by a Chiral HPLC-FD. In 243rd American Chemical Society National Meeting and Exposition (ACS Spring 2012), San Diego, U.S.A., 25-29 March 2012por
dc.identifier.urihttp://hdl.handle.net/10400.14/13238
dc.language.isoengpor
dc.subjectbiodegradationpor
dc.subjectchiralpor
dc.subjectpharmaceuticalspor
dc.titleBiodegradation of chiral pharmaceuticals by an activated sludge consortium followed by a Chiral HPLC-FDpor
dc.typeconference object
dspace.entity.typePublication
person.familyNameCastro
person.familyNameAfonso
person.familyNameTiritan
person.givenNamePaula
person.givenNameCarlos
person.givenNameMaria Elizabeth
person.identifier2013444
person.identifier1310409
person.identifier.ciencia-id7C1F-6C72-354A
person.identifier.ciencia-id6A10-3565-6158
person.identifier.ciencia-idD915-BFC0-FB3A
person.identifier.orcid0000-0001-8841-6606
person.identifier.orcid0000-0002-5731-5789
person.identifier.orcid0000-0003-3320-730X
person.identifier.ridM-8241-2013
person.identifier.ridI-5989-2015
person.identifier.ridK-9492-2014
person.identifier.scopus-author-id7102781782
person.identifier.scopus-author-id36145043600
person.identifier.scopus-author-id6602890981
rcaap.rightsopenAccesspor
rcaap.typeconferenceObjectpor
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relation.isAuthorOfPublication181a86a6-86a0-463c-b86e-d4e5669236da
relation.isAuthorOfPublication1ab8e8f5-cf82-4edd-89d8-46e5cca13e19
relation.isAuthorOfPublication.latestForDiscovery1ab8e8f5-cf82-4edd-89d8-46e5cca13e19

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