Repository logo
 
Publication

Bioactive extracts from brewer's spent grain

2020Journal article Restricted access
Simple item page
dc.contributor.authorBonifácio-Lopes, Teresa
dc.contributor.authorBoas, Ana Vilas
dc.contributor.authorCoscueta, Ezequiel R.
dc.contributor.authorCosta, Eduardo M.
dc.contributor.authorSilva, Sara
dc.contributor.authorCampos, Débora
dc.contributor.authorTeixeira, José A.
dc.contributor.authorPintado, Manuela
dc.date.accessioned2021-01-29T11:44:15Z
dc.date.available2021-01-29T11:44:15Z
dc.date.issued2020
dc.description.abstractIn this study antioxidant-rich extracts from brewer’s spent grain (BSG) extracted with solid-to-liquid extraction using different solvents water and ethanol and their mixtures at two ratios (80% ethanol:water (v/v) and 60% ethanol:water (v/v)) were characterized. Nutritional composition was evaluated for the extracts and for the solid residues obtained after extraction. Additionally, the extracts were analyzed for the total phenolic content and individual phenolic compounds and related biological properties including antioxidant capacity (ABTS; ORAC and DNA protection), antihypertensive capacity, antibacterial activity and antibiofilm capacity. Safety was also demonstrated through genotoxicity and cytotoxicity tests. The results obtained showed that while all the extracts exhibited high antioxidant capacity (except ethanolic extract), the highest values were obtained for the 60% ethanol:water extract. The identification of phenolic compounds using HPLC showed that catechin and vanillin were the main compounds identified with the highest concentration being obtained for 60% ethanol:water extraction. In the biological activity assays water and hydroethanolic extracts showed to be multifunctional (antioxidant and antihypertensive capacity, antibacterial and antibiofilm activity), the 80% ethanol:water presented better results in some assays. All were non-genotoxic, but the cytotoxicity was dependent on the extract concentration, with complete safe application for all up to 1 mg/mL. Therefore, this study shows the potential of a viable green solvent based and a low cost extraction recovery method of bioactive compounds from brewer’s spent grain.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBonifácio-Lopes, T., Boas, A. A. V., Coscueta, E. R., Costa, E. M., Silva, S., Campos, D., ... Pintado, M. (2020). Bioactive extracts from brewer's spent grain. Food & Functionpt_PT
dc.identifier.doi10.1039/d0fo01426ept_PT
dc.identifier.eissn2042-650X
dc.identifier.issn2042-6496
dc.identifier.pmid33001088
dc.identifier.urihttp://hdl.handle.net/10400.14/31813
dc.identifier.wosWOS:000580667100042
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherRoyal Society of Chemistrypt_PT
dc.relationNORTE-01-0145-FEDER- 000004pt_PT
dc.relationOCI-01-0145-FEDER-006684pt_PT
dc.relationCentre of Biological Engineering - University of Minho
dc.relationCentre for Biotechnology and Fine Chemistry
dc.subjectBrewer’s spent grainpt_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectAntioxidant activitypt_PT
dc.subjectBioactivitypt_PT
dc.subjectAntihypertensivept_PT
dc.titleBioactive extracts from brewer's spent grainpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCentre of Biological Engineering - University of Minho
oaire.awardTitleCentre for Biotechnology and Fine Chemistry
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FBIO%2F04469%2F2019/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F50016%2F2019/PT
oaire.citation.titleFood & Functionpt_PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameVilas Boas
person.familyNameCoscueta
person.familyNameCosta
person.familyNameSilva
person.familyNameCampos
person.familyNameTeixeira
person.familyNamePintado
person.givenNameAna
person.givenNameEzequiel
person.givenNameEduardo
person.givenNameSara
person.givenNameDébora
person.givenNameJosé
person.givenNameMaria Manuela
person.identifierD-8675-2016
person.identifier456608
person.identifier.ciencia-id4212-C7A2-9131
person.identifier.ciencia-id6614-705D-EBA7
person.identifier.ciencia-idB218-870B-98B5
person.identifier.ciencia-id1A16-FC5B-3468
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0002-9051-8123
person.identifier.orcid0000-0003-4496-2001
person.identifier.orcid0000-0003-3121-4514
person.identifier.orcid0000-0002-0896-9946
person.identifier.orcid0000-0003-0174-6640
person.identifier.orcid0000-0002-4918-3704
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridJ-7033-2016
person.identifier.ridA-6268-2012
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id56986455000
person.identifier.scopus-author-id55249865700
person.identifier.scopus-author-id55250923400
person.identifier.scopus-author-id13402823200
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1cf619c5-dbe8-4e22-a3ba-443778174c9c
relation.isAuthorOfPublicationf1f94059-86c8-4386-875f-a864386d54b4
relation.isAuthorOfPublication4f32e563-443f-4eff-8fea-e0916c20afa1
relation.isAuthorOfPublicatione235d930-fd32-4ee5-8588-8712efc83745
relation.isAuthorOfPublication9676a744-8335-428f-a861-3458cd7283f6
relation.isAuthorOfPublication9662078c-5f2c-4ea9-8037-0165b5e0cf5a
relation.isAuthorOfPublicationba387c7d-27c9-4016-895c-b35597e91ebc
relation.isAuthorOfPublication.latestForDiscovery4f32e563-443f-4eff-8fea-e0916c20afa1
relation.isProjectOfPublication8a1c14da-f7a2-488f-a72d-4257d7a8e3e9
relation.isProjectOfPublication1f76a7db-2520-482f-b56b-7e01ea36dd1f
relation.isProjectOfPublication.latestForDiscovery8a1c14da-f7a2-488f-a72d-4257d7a8e3e9

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Bioactive extracts from.pdf
Size:
1.79 MB
Format:
Adobe Portable Document Format
Download

Collections

CBQF - Contribuições em Revistas Científicas / Contribution to Journals