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Conventional and natural compounds for the treatment of dermatophytosis

dc.contributor.authorLopes, Ana I.
dc.contributor.authorTavaria, Freni K.
dc.contributor.authorPintado, Manuela E.
dc.date.accessioned2019-12-06T11:51:01Z
dc.date.available2019-12-06T11:51:01Z
dc.date.issued2020
dc.description.abstractDermatophytes are a group of pathogenic fungi that exclusively infect the stratum corneum of the skin, nails, and hair, causing dermatophytosis. Superficial skin infections caused by dermatophytes have increased in the last decades. There are conventional antifungals that treat these infections, such as terbinafine, fluconazole, and others. However, the limitations of these treatments (resistance, side effects and toxicity) along with the increasing over-prescription, the misuse of these antifungals and the high treatment costs led to the search for new, alternative, natural-based antifungal drugs. These have multiple mechanisms of action, which works to their advantage, making it difficult for a fungus to create resistance mechanisms against all of them at the same time. The main objective of this work is to provide a state-of-the-art review on dermatophytes, dermatophytosis, and the existing treatments, both conventional and natural, such as chitosan and essential oils.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationLopes, A. I., Tavaria, F. K., Pintado, M. E. (2020). Conventional and natural compounds for the treatment of dermatophytosis. Medical mycology, 58, 707–720pt_PT
dc.identifier.doi10.1093/mmy/myz116pt_PT
dc.identifier.eid85089128386
dc.identifier.eissn1460-2709
dc.identifier.issn1369-3786
dc.identifier.pmid31773153
dc.identifier.urihttp://hdl.handle.net/10400.14/28956
dc.identifier.wos000593378700001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford University Presspt_PT
dc.relationNORTE/01/0145/Feder/000012
dc.subjectDermatophytespt_PT
dc.subjectDermatophytosispt_PT
dc.subjectAntifungalspt_PT
dc.subjectChitosanpt_PT
dc.subjectEssential oilspt_PT
dc.titleConventional and natural compounds for the treatment of dermatophytosispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F50016%2F2013/PT
oaire.citation.endPage720
oaire.citation.startPage707
oaire.citation.titleMedical Mycologypt_PT
oaire.citation.volume58
oaire.fundingStream5876
person.familyNameKekhasharú Tavaria
person.familyNamePintado
person.givenNameFreni
person.givenNameMaria Manuela
person.identifier456608
person.identifier.ciencia-id1B15-5DAD-7B27
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0002-6273-6668
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id6602645613
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicatione42f563a-5b1e-4586-b302-efabe7ce07da
relation.isAuthorOfPublicationba387c7d-27c9-4016-895c-b35597e91ebc
relation.isAuthorOfPublication.latestForDiscoveryba387c7d-27c9-4016-895c-b35597e91ebc
relation.isProjectOfPublication3fe5970e-de39-42f7-a29d-18521b591a09
relation.isProjectOfPublication.latestForDiscovery3fe5970e-de39-42f7-a29d-18521b591a09

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