Publication
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial
| dc.contributor.author | Azevedo, Luís | |
| dc.contributor.author | Correia, André | |
| dc.contributor.author | Almeida, Carlos F. | |
| dc.contributor.author | Molinero-Mourelle, Pedro | |
| dc.contributor.author | Correia, Maria | |
| dc.contributor.author | Hisghsmith, Jaime Del Río | |
| dc.date.accessioned | 2023-10-11T13:06:20Z | |
| dc.date.available | 2023-10-11T13:06:20Z | |
| dc.date.issued | 2021-02-08 | |
| dc.description.abstract | To assess the clinical efficacy of a novel organic olive oil-based denture adhesive and its effect on Candida Albicans growth in maxillary edentulous individuals wearing complete dentures. Individuals were selected from two Dental Schools in Portugal and Spain. Twenty-eight complete dentures were relined, following a standardized protocol. The novel product (Test) was compared with a commercialized adhesive (Control) and Vaseline (Placebo) randomly assigned in a crossstudy design. The retention resistance was measured with a Gnathometer and a dynamometer, the patient related outcome evaluations with a 5-points questionnaire and the Candida albicans growth in a Sabouraud dextrose agar (SDA) medium in order to evaluate differences between the placebo and experimental product. Twenty-three participants were included. Dynamometer evaluation showed significant differences between not using a denture adhesive and using either (experimental, p = .03; control, p = .04), no significant differences between the two adhesives (p > .05). In the subjective analysis, the experimental adhesive showed a significantly longer effectiveness (p = .001); the control reported better results at taste (p = .03) in chewing (p = .001). The test adhesive showed better (p < .001) Candida albicans growth inhibition. The experimental adhesive showed longer effectiveness than the control and placebo with a better inhibition capacity for the growth of Candida albicans, patients reported better abilities for speech, chewing, taste and retirement in the control adhesive. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.20944/preprints202102.0222.v1 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.14/42838 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | Preprints.org | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Prosthodontics | pt_PT |
| dc.subject | Edentulism | pt_PT |
| dc.subject | Elderly | pt_PT |
| dc.subject | Complete Denture | pt_PT |
| dc.subject | Candida Albicans | pt_PT |
| dc.subject | Antimicrobial activity | pt_PT |
| dc.title | Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial | pt_PT |
| dc.type | working paper | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 10 | pt_PT |
| oaire.citation.startPage | 1 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | workingPaper | pt_PT |