Publication
Role of antiseptics in the prevention and treatment of infections in nursing homes
| dc.contributor.author | Alves, P. J. | |
| dc.contributor.author | Gryson, L. | |
| dc.contributor.author | Hajjar, J. | |
| dc.contributor.author | Lepelletier, D. | |
| dc.contributor.author | Reners, M. | |
| dc.contributor.author | Salazar, J. Rodríguez | |
| dc.contributor.author | Simon, A. | |
| dc.date.accessioned | 2022-10-19T15:03:13Z | |
| dc.date.available | 2022-10-19T15:03:13Z | |
| dc.date.issued | 2023-01-01 | |
| dc.description.abstract | Inadequate infection control, wound care, and oral hygiene protocols in nursing homes provide challenges to residents’ quality of life. Based on the outcomes from a focus group meeting and a literature search, this narrative review evaluates the current and potential roles of antiseptics within nursing home infection management procedures. We examine contemporary strategies and concerns within the management of meticillin-resistant Staphylococcus aureus (MRSA; including decolonization regimes), chronic wound care, and oral hygiene, and review the available data for the use of antiseptics, with a focus on povidone-iodine. Compared with chlorhexidine, polyhexanide, and silver, povidone-iodine has a broader spectrum of antimicrobial activity, with rapid and potent activity against MRSA and other microbes found in chronic wounds, including biofilms. As no reports of bacterial resistance or cross-resistance following exposure to povidone-iodine exist, it may be preferable for MRSA decolonization compared with mupirocin and chlorhexidine, which can cause resistant MRSA strains. Povidone-iodine oral products have greater efficacy against oral pathogens compared with other antiseptics such as chlorhexidine mouthwash, highlighting the clinical benefit of povidone-iodine in oral care. Additionally, povidone-iodine-based products, including mouthwash, have demonstrated rapid in vitro virucidal activity against SARS-CoV-2 and may help reduce its transmission if incorporated into nursing home coronavirus 2019 control protocols. Importantly, povidone-iodine activity is not adversely affected by organic material, such as that found in chronic wounds and the oral cavity. Povidone-iodine is a promising antiseptic agent for the management of infections in the nursing home setting, including MRSA decolonization procedures, chronic wound management, and oral care. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.1016/j.jhin.2022.09.021 | pt_PT |
| dc.identifier.eid | 85141989584 | |
| dc.identifier.issn | 0195-6701 | |
| dc.identifier.pmid | 36216172 | |
| dc.identifier.uri | http://hdl.handle.net/10400.14/39156 | |
| dc.identifier.wos | 001020814700007 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | Povidone-iodine | pt_PT |
| dc.subject | Decolonization | pt_PT |
| dc.subject | Oral hygiene | pt_PT |
| dc.subject | Chronic wound | pt_PT |
| dc.subject | Coronavirus 2019 | pt_PT |
| dc.subject | Meticillin-resistant Staphylococcus aureus | pt_PT |
| dc.title | Role of antiseptics in the prevention and treatment of infections in nursing homes | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 69 | |
| oaire.citation.startPage | 58 | |
| oaire.citation.title | Journal of Hospital Infection | pt_PT |
| oaire.citation.volume | 131 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |