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Assessment of baby Bibs. GC-MS screening, migration into saliva and insight of toxicity with QSAR tools

2020Journal article Open access
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dc.contributor.authorRajbux, Chandisree
dc.contributor.authorPereira, Joel
dc.contributor.authorSelbourne, Maria do Céu
dc.contributor.authorCosta-Pinto, Ana Rita
dc.contributor.authorPoças, Fátima
dc.date.accessioned2019-10-22T14:18:46Z
dc.date.available2019-10-22T14:18:46Z
dc.date.issued2020
dc.description.abstractPlastic baby Bibs are, according to the European legislation, food contact materials. Therefore, compositional and migration limits applicable to plastics should be observed. This work aimed at identifying potential migrants in Bibs from European market and determining the migration into artificial saliva. Bibs were subjected to screening analyses (GC-MS). Thirty substances non-authorised in European or Swiss legislation were detected: phthalates, light stabilizers, flame retardants and photoinitiators. Irgacure 184, Cyclohexanone, Tinuvin 770, Isophorone and 9-Octadecenamide, (Z)- were detected in saliva after contact with selected Bibs. The migration values render two samples noncompliant although results should be interpreted with caution given the experimental conditions. In order to gain insight on the toxicity of migrants, QSAR tools were applied. Substances non-evaluated or not-listed were analysed with free software regarding their Cramer class (ToxTree and their predicted mutagenicity, carcinogenicity and developmental toxicity (VEGA). Results indicate that surveillance is required: monitoring Bibs'compliance, application of GMPs and traceability.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.citationRajbux, C., Pereira, J., Selbourne, M. do C., Costa-Pinto, A. R., & Poças, F. (2020). Assessment of baby Bibs. GC-MS screening, migration into saliva and insight of toxicity with QSAR tools. Food Control, 109, 106951. https://doi.org/10.1016/j.foodcont.2019.106951pt_PT
dc.identifier.doi10.1016/j.foodcont.2019.106951pt_PT
dc.identifier.eid85073811587
dc.identifier.eissn1873-7129
dc.identifier.issn0956-7135
dc.identifier.urihttp://hdl.handle.net/10400.14/28483
dc.identifier.wos000500052400061
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectFood contact materialspt_PT
dc.subjectBaby bibspt_PT
dc.subjectMigrationpt_PT
dc.subjectQSARpt_PT
dc.subjectSafety evaluationpt_PT
dc.subjectPlasticspt_PT
dc.subjectNIASpt_PT
dc.titleAssessment of baby Bibs. GC-MS screening, migration into saliva and insight of toxicity with QSAR toolspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFood Controlpt_PT
oaire.citation.volume109
person.familyNamePereira
person.familyNameCosta-Pinto
person.familyNamePoças
person.givenNameJoel
person.givenNameAna Rita
person.givenNameMaria de Fátima
person.identifier.ciencia-id7811-97CE-2BD9
person.identifier.ciencia-id1313-66B7-2A1E
person.identifier.ciencia-id1513-5F90-0B67
person.identifier.orcid0000-0003-4607-5289
person.identifier.orcid0000-0002-4764-8539
person.identifier.orcid0000-0002-6598-6515
person.identifier.ridI-7483-2013
person.identifier.scopus-author-id55426277700
person.identifier.scopus-author-id24390737500
person.identifier.scopus-author-id15127714500
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationdc6e1f27-09e1-485d-b9c5-1daa05e5af9f
relation.isAuthorOfPublication01f178ed-80a7-468a-8cd4-a96e2f4af148
relation.isAuthorOfPublicationdca9a545-c7be-41fd-802b-b608d9d240eb
relation.isAuthorOfPublication.latestForDiscoverydca9a545-c7be-41fd-802b-b608d9d240eb

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