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Effects of whey peptide extract on the growth of probiotics and gut microbiota

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dc.contributor.authorYu, Ya-Ju
dc.contributor.authorAmorim, Manuela
dc.contributor.authorMarques, Cláudia
dc.contributor.authorCalhau, Conceição
dc.contributor.authorPintado, M. E.
dc.date.accessioned2017-10-16T15:22:14Z
dc.date.available2017-10-16T15:22:14Z
dc.date.issued2016
dc.description.abstractWhey peptide extract with molecular weight below 1 kDa was investigated in microplate assay, and viable cells, as well as metabolic activity were determined to evaluate augmented growth of probiotic bacteria (Lactobacillus acidophilus and Bifidobacterium animalis). Results illustrated that whey peptide extract 1% (w/v) has the capacity to stimulate the proliferation of both probiotic bacteria tested, further supported by the faster generation of metabolic products. The effect of whey peptide extract on the modulation of gut microbiota was also examined inWistar rats fed either with a standard or a high-fat diet, assessed via 16S ribosomal RNA expression of gut microbiota by quantitative PCR. Relative abundance of Lactobacillus spp., Bifidobacterium spp. and Bacteroidetes was significantly increased by whey peptide extract in rats fed with a standard diet. These results highlight an additional unexploited positive effect of whey peptide extract on gut microbiota modulation.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationYU, Ya-Ju; AMORIM, Manuela; MARQUES, Cláudia; CALHAU, Conceição; PINTADO, M. E. - Effects of whey peptide extract on the growth of probiotics and gut microbiota. Journal of Functional Foods. SSN: 1756-4646. Vol. 21 (2016), p. 507-516pt_PT
dc.identifier.doi10.1016/j.jff.2015.10.035
dc.identifier.eid84957900073
dc.identifier.urihttp://hdl.handle.net/10400.14/23116
dc.identifier.wos000371281900049
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier
dc.subjectGut microbiotapt_PT
dc.subjectPrebioticspt_PT
dc.subjectProbioticspt_PT
dc.subjectWhey peptide extractpt_PT
dc.titleEffects of whey peptide extract on the growth of probiotics and gut microbiotapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PEst-OE%2FEQB%2FLA0016%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F81901%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F93073%2F2013/PT
oaire.citation.titleJournal of Functional Foodspt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStreamSFRH
oaire.fundingStreamSFRH
person.familyNameAmorim
person.familyNameMarques
person.familyNameCalhau
person.familyNamePintado
person.givenNameMaria Manuela
person.givenNameCláudia
person.givenNameConceição
person.givenNameMaria Manuela
person.identifier456608
person.identifier.ciencia-id791D-E9BA-D432
person.identifier.ciencia-id2110-0420-1717
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person.identifier.orcid0000-0002-1485-0423
person.identifier.orcid0000-0002-8365-7934
person.identifier.orcid0000-0001-9567-3379
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridL-4327-2014
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id55293251500
person.identifier.scopus-author-id6701578877
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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