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Advisor(s)
Abstract(s)
Whey peptide extract with molecular weight below 1 kDa was investigated in microplate
assay, and viable cells, as well as metabolic activity were determined to evaluate augmented
growth of probiotic bacteria (Lactobacillus acidophilus and Bifidobacterium animalis).
Results illustrated that whey peptide extract 1% (w/v) has the capacity to stimulate the proliferation
of both probiotic bacteria tested, further supported by the faster generation of
metabolic products. The effect of whey peptide extract on the modulation of gut microbiota
was also examined inWistar rats fed either with a standard or a high-fat diet, assessed via
16S ribosomal RNA expression of gut microbiota by quantitative PCR. Relative abundance
of Lactobacillus spp., Bifidobacterium spp. and Bacteroidetes was significantly increased by whey
peptide extract in rats fed with a standard diet. These results highlight an additional
unexploited positive effect of whey peptide extract on gut microbiota modulation.
Description
Keywords
Gut microbiota Prebiotics Probiotics Whey peptide extract
Citation
YU, Ya-Ju; AMORIM, Manuela; MARQUES, Cláudia; CALHAU, Conceição; PINTADO, M. E. - Effects of whey peptide extract on the growth of probiotics and gut microbiota. Journal of Functional Foods. SSN: 1756-4646. Vol. 21 (2016), p. 507-516
Publisher
Elsevier