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Evidences and perspectives in the utilization of CLNA isomers as bioactive compound in foods

dc.contributor.authorFontes, Ana L.
dc.contributor.authorPimentel, Lígia
dc.contributor.authorSimões, Catarina D.
dc.contributor.authorGomes, Ana M. P.
dc.contributor.authorRodríguez-Alcalá, Luís M.
dc.date.accessioned2017-10-12T14:19:50Z
dc.date.available2017-10-12T14:19:50Z
dc.date.issued2017
dc.description.abstractConjugated linolenic acid (CLNA) isomers are promising lipids due to their similarities with CLA but exerting their bioactivity at lower doses; some isomers also belong to the omega 3 family. This review aims to summarize the state of the art about the utilization of CLNA as a functional ingredient. Indeed, in vitro and in vivo studies reported that CLNA exerted anti-cancer, anti-inflammatory, anti-obese and antioxidant activities. However, CLNA has not been tested in humans yet. These compounds are naturally present in meat and milk fat from ruminants but the highest concentrations are found in vegetable oils. Their incorporation in foodstuffs is one of the most effective strategies to elaborate CLNA-enriched products together with the microbiological production. Lactobacilli, propionibacteria and bifidobacteria strains have been assayed to produce CLNA isomers but at the current moment there are not high CLNA concentration products elaborated using these strains. Furthermore, it is known that CLNA are highly prone to oxidation when compared with linoleic acid and CLA but it is unknown the possible effects of elaboration and storage on high CLNA products. The utilization of CLNA as a functional compound remains still a challenge that requires more research to address all the technological and bioactivity aspects about it.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationFONTES, Ana L.; PIMENTEL, Lígia; SIMÕES, Catarina D.; GOMES, Ana M. P.; RODRÍGUEZ-ALCALÁ, Luís M. - Evidences and perspectives in the utilization of CLNA isomers as bioactive compound in foods. Critical Reviews in Food Science and Nutrition. ISSN 1549-7852. (2016), 51 p.pt_PT
dc.identifier.doi10.1080/10408398.2015.1063478pt_PT
dc.identifier.eid85018429588
dc.identifier.eissn1549-7852
dc.identifier.issn1040-8398
dc.identifier.pmid27222914
dc.identifier.urihttp://hdl.handle.net/10400.14/23049
dc.identifier.wos000400511500009
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francis
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCLNA-enriched productspt_PT
dc.subjectMicrobiological productionpt_PT
dc.subjectBioactivitypt_PT
dc.subjectStabilitypt_PT
dc.subjectSafetypt_PT
dc.titleEvidences and perspectives in the utilization of CLNA isomers as bioactive compound in foodspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2622
oaire.citation.issue12
oaire.citation.startPage2611
oaire.citation.titleCritical Reviews in Food Science and Nutritionpt_PT
oaire.citation.volume57
person.familyNameFontes
person.familyNamePimentel
person.familyNameSimões
person.familyNameGomes
person.familyNameRodríguez-Alcalá
person.givenNameAna Luiza
person.givenNameLígia
person.givenNameCatarina
person.givenNameAna Maria
person.givenNameLuis Miguel
person.identifier534450
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person.identifier.ridK-3254-2014
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person.identifier.scopus-author-id57000067200
person.identifier.scopus-author-id22035944100
person.identifier.scopus-author-id57190668768
person.identifier.scopus-author-id19337562900
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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