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Histological assessment of bone regeneration in the maxilla with homologous bone graft: a feasible option for maxillary bone reconstruction

dc.contributor.authorMotta, Sergio Henrique Gonçalves
dc.contributor.authorSoares, Ana Paula Ramos
dc.contributor.authorFernandes, Juliana Campos Hasse
dc.contributor.authorFernandes, Gustavo Vicentis Oliveira
dc.date.accessioned2024-02-14T14:06:31Z
dc.date.available2024-02-14T14:06:31Z
dc.date.issued2024
dc.description.abstractBone biomaterials have been increasingly used to reconstruct maxillary atrophic ridges. Thus, the aim of this study was to evaluate bone reconstruction in the maxilla using a homologous cortico-cancellous FFB (lyophilized) graft and verify its reliability. Eight individuals were included from 2014 to 2018. The first surgery was performed to install homologous bone blocks in the maxilla. The period of the second intervention varied between 5 months and 15 days to 11 months (≈7.93 months). The biopsies were taken from the central region of the matured graft during the surgery for implant placement. All patients presented clinical and radiographic conditions for the installation of dental implants. There was a 100% of survival rate. The histological assessment showed that the homologous block bone graft was an osteoconductive biomaterial, with connective tissue present, and newly formed bone juxtaposed on its surface. There were bone trabeculae with osteocytes and active osteoblasts with connective tissue in the mineralization process; the remodeling process can be found through the reverse lines. A limited focus of necrosis with fibrosis was detected, with small resorption and areas of inflammatory infiltrate, but without clinical significance. The homologous block bone graft can be considered a feasible option to substitute the autogenous bone graft (gold standard), with predictable clinical and favorable histological results. The patients had a shorter surgical period, low morbidity, and an unlimited amount of biomaterial available at an accessible cost.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.32604/jrm.2023.043940pt_PT
dc.identifier.eid85184149047
dc.identifier.issn2164-6325
dc.identifier.urihttp://hdl.handle.net/10400.14/43955
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAllogenouspt_PT
dc.subjectAutogenouspt_PT
dc.subjectBone graftpt_PT
dc.subjectHistologypt_PT
dc.subjectHomologouspt_PT
dc.subjectRegenerationpt_PT
dc.titleHistological assessment of bone regeneration in the maxilla with homologous bone graft: a feasible option for maxillary bone reconstructionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage148pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage131pt_PT
oaire.citation.titleJournal of Renewable Materialspt_PT
oaire.citation.volume12pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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