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Strategy for the simulation of batch reactors when the enzyme-catalyzed reaction is accompanied by enzyme deactivation

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The balance equations pertaining to the modelling of batch reactors performing an enzyme-catalyzed reaction in the presence of enzyme deactivation are developed. The functional form of the solution for the general situation where both the rate of the enzyme-catalyzed reaction and the rate of enzyme deactivation are dependent on the substrate concentration is obtained, as well as the condition that applies if a maximum conversion of substrate is sought. Finally, two examples of practical interest are explored to emphasize the usefulness of the analysis presented.

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MALCATA, F.X. - Strategy for the simulation of batch reactors when the enzyme-catalyzed reaction is accompanied by enzyme deactivation. Bioprocess and Biosystems Engineering. ISSN 1615-7605. 11:1 (1994) 23-28

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Springer Verlag

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