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Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin

2021-09-14Journal article Open access
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dc.contributor.authorCoscueta, Ezequiel R.
dc.contributor.authorBrassesco, Maria Emilia
dc.contributor.authorPintado, Manuela
dc.date.accessioned2021-09-20T11:33:53Z
dc.date.available2021-09-20T11:33:53Z
dc.date.issued2021-09-14
dc.description.abstractConsiderable amounts of fish processing by-products are discarded each year. About 30% of this material may be skin and bone. Fish skin has more than 80% of its total protein content as collagen. Furthermore, in recent years, there has been a growing demand for collagen-based peptides due to their beneficial health effects. So, the objective of the present study was to optimise the obtaining bioactive hydrolysates from salt-cured cod skin using the protease Bromelain at 0.5% (w/w) concentration. This study developed a sustainable process that consumes less time and energy and uses an alternative source as raw material. In addition, bromelain allows hydrolysates with important antioxidant (ORAC, 514 μmol Trolox Equivalent/g protein) and antihypertensive activities (inhibition of ACE, IC50 of 166 μg protein/mL) as well as excellent biocompatibility with dermal and subcutaneous cells.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/app11188538pt_PT
dc.identifier.eid85115099262
dc.identifier.issn2076-3417
dc.identifier.urihttp://hdl.handle.net/10400.14/34996
dc.identifier.wos000699716400001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAtlantic cod skinpt_PT
dc.subjectEnzymatic hydrolysispt_PT
dc.subjectCollagenpt_PT
dc.subjectFishery by-productspt_PT
dc.subjectBioactive peptidespt_PT
dc.subjectBromelainpt_PT
dc.subjectAntioxidantpt_PT
dc.subjectAntihypertensivept_PT
dc.titleCollagen-based bioactive bromelain hydrolysate from salt-cured cod skinpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue18pt_PT
oaire.citation.titleApplied Sciences (Switzerland)pt_PT
oaire.citation.volume11pt_PT
person.familyNameCoscueta
person.familyNameBrassesco
person.familyNamePintado
person.givenNameEzequiel
person.givenNameMaria Emilia
person.givenNameMaria Manuela
person.identifier456608
person.identifier.ciencia-id6614-705D-EBA7
person.identifier.ciencia-id4819-BAD3-AF07
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0003-4496-2001
person.identifier.orcid0000-0001-9027-4643
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridJ-7033-2016
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id56986455000
person.identifier.scopus-author-id57190497489
person.identifier.scopus-author-id7004483898
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationf1f94059-86c8-4386-875f-a864386d54b4
relation.isAuthorOfPublication5628eda7-1d5d-48b4-840b-0978dcb28fa9
relation.isAuthorOfPublicationba387c7d-27c9-4016-895c-b35597e91ebc
relation.isAuthorOfPublication.latestForDiscoveryba387c7d-27c9-4016-895c-b35597e91ebc

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