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Transforming healthcare: treatment of inflammatory bowel disease with Bbocatalytic nanobots
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Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, affects over seven million individuals globally, presenting significant healthcare and economic challenges (1). The inflamed gut microenvironment is characterized by excessive reactive oxygen species (ROS), which exacerbates mucosal damage (2). To address these limitations, a modular polymeric nanobot (NB) system is under development, with each module offering distinct functionalities. This study focuses on designing the NB core to mitigate oxidative stress and encapsulate bioactive compounds, laying the groundwork for subsequent modules that will enhance stability, navigation, and targeted delivery along the gastrointestinal (GI) tract.
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Citação
Sousa, A. S., Mayer, A., Reis, C., & Pintado, M. M. et al. (2025). Transforming healthcare: rreatment of inflammatory bowel disease with Bbocatalytic nanobots. 1-3. Abstract from CRS 2025 Annual Meeting & Exposition, Philadelphia, PA, Pennsylvania, United States.