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A comparison of the temporary placement of 3 different self-expanding stents for the treatment of refractory benign esophageal strictures: a prospective multicentre study

2012-06-12Journal article Open access
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dc.contributor.authorCanena, Jorge Manuel T.
dc.contributor.authorLiberato, Manuel José A.
dc.contributor.authorRio-Tinto, Ricardo António N.
dc.contributor.authorPinto-Marques, Pedro M.
dc.contributor.authorRomão, Carlos Manuel M.
dc.contributor.authorCoutinho, António Vasco Mello Pereira
dc.contributor.authorNeves, Beatriz Alda Henriques Costa
dc.contributor.authorSantos-Silva, Maria Filipa Costa Neves
dc.date.accessioned2021-10-15T13:48:55Z
dc.date.available2021-10-15T13:48:55Z
dc.date.issued2012-06-12
dc.description.abstractBackground: Refractory benign esophageal strictures (RBESs) have been treated with the temporary placement of different self-expanding stents with conflicting results. We compared the clinical effectiveness of 3 types of stents: self-expanding plastic stents (SEPSs), biodegradable stents, and fully covered self-expanding metal stents (FCSEMSs), for the treatment of RBES.Methods: This study prospectively evaluated 3 groups of 30 consecutive patients with RBESs who underwent temporary placement of either SEPSs (12 weeks, n = 10), biodegradable stents (n = 10) or FCSEMSs (12 weeks, n = 10). Data were collected to analyze the technical success and clinical outcome of the stents as evaluated by recurrent dysphagia, complications and reinterventions.Results: Stent implantation was technically successful in all patients. Migration occurred in 11 patients: 6 (60%) in the SEPS group, 2 (20%) in the biodegradable group and 3 (30%) in the FCSEMS group (P = 0.16). A total of 8/30 patients (26.6%) were dysphagia-free after the end of follow-up: 1 (10%) in the SEPS group, 3 (30%) in the biodegradable group and 4 (40%) in the FCSEMS group (P = 0.27). More reinterventions were required in the SEPS group (n = 24) than in the biodegradable group (n = 13) or the FCSEMS group (n = 13) (P = 0.24). Multivariate analysis showed that stricture length was significantly associated with higher recurrence rates after temporary stent placement (HR = 1.37; 95% CI = 1.08-1.75; P = 0.011).Conclusions: Temporary placement of a biodegradable stent or of a FCSEMS in patients with RBES may lead to long-term relief of dysphagia in 30 and 40% of patients, respectively. The use of SEPSs seems least preferable, as they are associated with frequent stent migration, more reinterventions and few cases of long-term improvement. Additionally, longer strictures were associated with a higher risk of recurrence.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1186/1471-230X-12-70pt_PT
dc.identifier.eid84866373226
dc.identifier.issn1471-230X
dc.identifier.pmid22691296
dc.identifier.urihttp://hdl.handle.net/10400.14/35574
dc.identifier.wos000308997100001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBiodegradable stentspt_PT
dc.subjectExpandable esophageal stentspt_PT
dc.subjectFully covered self-expanding metal stentspt_PT
dc.subjectRefractory benign esophageal stricturespt_PT
dc.subjectSelf-expanding plastic stentspt_PT
dc.titleA comparison of the temporary placement of 3 different self-expanding stents for the treatment of refractory benign esophageal strictures: a prospective multicentre studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBMC Gastroenterologypt_PT
oaire.citation.volume12pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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