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The role of health preconditions on COVID-19 deaths in Portugal: evidence from surveillance data of the first 20293 infection cases

2020-08Journal article Open access
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dc.contributor.authorNogueira, Paulo Jorge
dc.contributor.authorNobre, Miguel de Araújo
dc.contributor.authorCosta, Andreia
dc.contributor.authorRibeiro, Ruy M.
dc.contributor.authorFurtado, Cristina
dc.contributor.authorNicolau, Leonor Bacelar
dc.contributor.authorCamarinha, Catarina
dc.contributor.authorLuís, Márcia
dc.contributor.authorAbrantes, Ricardo
dc.contributor.authorCarneiro, António Vaz
dc.date.accessioned2021-03-17T17:29:56Z
dc.date.available2021-03-17T17:29:56Z
dc.date.issued2020-08
dc.description.abstractBackground: It is essential to study the effect of potential co-factors on the risk of death in patients infected by COVID-19. The identification of risk factors is important to allow more efficient public health and health services strategic interventions with a significant impact on deaths by COVID-19. This study aimed to identify factors associated with COVID-19 deaths in Portugal. Methods: A national dataset with the first 20,293 patients infected with COVID-19 between 1 January and 21 April 2020 was analyzed. The primary outcome measure was mortality by COVID-19, measured (registered and confirmed) by Medical Doctors serving as health delegates on the daily death registry. A logistic regression model using a generalized linear model was used for estimating Odds Ratio (OR) with 95% confidence intervals (95% CI) for each potential risk indicator. Results: A total of 502 infected patients died of COVID-19. The risk factors for increased odds of death by COVID-19 were: sex (male: OR = 1.47, ref = female), age ((56-60) years, OR = 6.01; (61-65) years, OR = 10.5; (66-70) years, OR = 20.4; (71-75) years, OR = 34; (76-80) years, OR = 50.9; (81-85) years, OR = 70.7; (86-90) years, OR = 83.2; (91-95) years, OR = 91.8; (96-104) years, OR = 140.2, ref = (0-55)), Cardiac disease (OR = 2.86), Kidney disorder (OR = 2.95), and Neuromuscular disorder (OR = 1.58), while condition (None (absence of precondition); OR = 0.49) was associated with a reduced chance of dying after adjusting for other variables of interest. Conclusions: Besides age and sex, preconditions justify the risk difference in mortality by COVID-19.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/jcm9082368pt_PT
dc.identifier.eid85097273865
dc.identifier.issn2077-0383
dc.identifier.pmcPMC7464004
dc.identifier.pmid32722159
dc.identifier.urihttp://hdl.handle.net/10400.14/32253
dc.identifier.wos000567321900001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCOVID-19pt_PT
dc.subjectMortalitypt_PT
dc.subjectDemographicspt_PT
dc.subjectSystemic conditionpt_PT
dc.subjectCardiovascularpt_PT
dc.subjectCancerpt_PT
dc.subjectDiabetespt_PT
dc.subjectEpidemiologypt_PT
dc.subjectLogistic regressionpt_PT
dc.subjectArea under the curvept_PT
dc.titleThe role of health preconditions on COVID-19 deaths in Portugal: evidence from surveillance data of the first 20293 infection casespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleJournal of Clinical Medicinept_PT
oaire.citation.volume9pt_PT
person.familyNameNogueira
person.familyNamede Araújo Nobre
person.familyNameCosta
person.familyNameBacelar-Nicolau
person.familyNameMacedo Abrantes
person.givenNamePaulo Jorge
person.givenNameMiguel
person.givenNameAndreia
person.givenNameLeonor
person.givenNameRicardo
person.identifier1013768
person.identifier617615
person.identifier1154144
person.identifier.ciencia-id2410-2DCC-F213
person.identifier.ciencia-id2F12-4A0D-AC2A
person.identifier.ciencia-id071D-4FEB-416D
person.identifier.ciencia-id4D1C-4B92-5636
person.identifier.ciencia-id5C1C-2581-6186
person.identifier.orcid0000-0001-8316-5035
person.identifier.orcid0000-0002-7084-8301
person.identifier.orcid0000-0002-2727-4402
person.identifier.orcid0000-0003-0421-1262
person.identifier.orcid0000-0001-8958-7407
person.identifier.ridAAR-5605-2020
person.identifier.ridV-5277-2019
person.identifier.ridC-5030-2014
person.identifier.scopus-author-id7005428250
person.identifier.scopus-author-id16686056100
person.identifier.scopus-author-id57202310047
person.identifier.scopus-author-id14519023400
person.identifier.scopus-author-id57246542000
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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