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In vitro screening for antimicrobial activity of chitosans and Chitooligosaccharides, aiming at potential uses in functional textiles

dc.contributor.authorFernandes, João C.
dc.contributor.authorTavaria, Freni K.
dc.contributor.authorFonseca, Susana C.
dc.contributor.authorRamos, Óscar S.
dc.contributor.authorPintado, Manuela E.
dc.contributor.authorMalcata, F. Xavier
dc.date.accessioned2010-10-06T14:57:39Z
dc.date.available2010-10-06T14:57:39Z
dc.date.issued2010
dc.description.abstractAntimicrobial finishing of textiles has been found to be an economical way to prevent (or treat) skin disorders. Hence, this research effort was aimed at elucidating the relationship between molecular weight (MW) of chitosan and its antimicrobial activity upon six dermal reference microorganisms, as well as the influence of the interactions with cotton fabrics on said activity. Using 3 chitosans with different MW, as well as two chitooligosaccharide (COS) mixtures, a relevant antimicrobial effect was observed by 24 h for the six microorganisms tested; it was apparent that the antimicrobial effect is strongly dependent on the type of target microorganism and on the MW of chitosan – being higher for lower MW in the case of E. coli, K. pneumoniae and P. aeruginosa, and the reverse in the case of both Gram-positive bacteria. Furthermore, a strong anti-fungal effect was detectable upon C. albicans, resembling the action over Gram-positive bacteria. Interactions with cotton fabric resulted in a loss of COS activity when compared with cultured media, relative to the effect over Gram-negative bacteria. However, no significant differences for the efficacy of all the 5 compounds were observed by 4 h. The three chitosans possessed a higher antimicrobial activity when impregnated onto the fabric, and presented a similar effect on both Gram-positive bacteria and yeast, in either matrix. Pseudomonas aeruginosa showed to be the most resistant microorganism to all five compounds.por
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.4014/jmb.0904.04038
dc.identifier.eid77649220273
dc.identifier.eissn1738-8872
dc.identifier.issn1017-7825
dc.identifier.pmid20208434
dc.identifier.urihttp://hdl.handle.net/10400.14/2667
dc.identifier.wos000275103400011
dc.language.isoengpor
dc.publisherThe Korean Society for Applied Microbiologypor
dc.subjectMolecular weightpor
dc.subjectBiopolymerspor
dc.subjectSkin-borne microorganismspor
dc.titleIn vitro screening for antimicrobial activity of chitosans and Chitooligosaccharides, aiming at potential uses in functional textilespor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage318
oaire.citation.issue2
oaire.citation.startPage311
oaire.citation.titleJournal of microbiology and biotechnology
oaire.citation.volume20
person.familyNameFernandes
person.familyNameKekhasharú Tavaria
person.familyNameCaldas-Fonseca
person.familyNameRamos
person.familyNamePintado
person.familyNameMalcata
person.givenNameJoão
person.givenNameFreni
person.givenNameSusana
person.givenNameOscar
person.givenNameMaria Manuela
person.givenNameFrancisco
person.identifier456608
person.identifier.ciencia-id881D-7FFD-DD7D
person.identifier.ciencia-id1B15-5DAD-7B27
person.identifier.ciencia-idCA17-1DC3-74DF
person.identifier.ciencia-id5C19-49E0-96EF
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.ciencia-id1B13-38A5-35F5
person.identifier.orcid0000-0003-1556-1698
person.identifier.orcid0000-0002-6273-6668
person.identifier.orcid0000-0003-4793-5965
person.identifier.orcid0000-0002-7627-189X
person.identifier.orcid0000-0002-0760-3184
person.identifier.orcid0000-0003-3073-1659
person.identifier.ridK-3126-2013
person.identifier.ridB-2880-2012
person.identifier.ridM-3981-2013
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id35274726800
person.identifier.scopus-author-id6602645613
person.identifier.scopus-author-id7005476572
person.identifier.scopus-author-id54889028400
person.identifier.scopus-author-id7004483898
person.identifier.scopus-author-id7102542478
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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