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Advisor(s)
Abstract(s)
Gut bacterium Akkermansia muciniphila has been recognized as a new potential probiotic due to promising outcomes in the prevention and treatment of several human diseases. However, despite its multiple beneficial effects, its viability is compromised by the presence of oxygen. This has so far precluded its application namely in the development of nutraceutical/therapeutic formulations. In order to enhance growth of A. muciniphila and its survival through lyophilisation and storage at air ambient, formulation strategies are presented based on use of prebiotic compounds, antioxidants and cryoprotectants. According to our best knowledge, there is no information regarding lyophilisation procedures involving A. muciniphila as well as
its subsequent storage at ambient air.
Description
Keywords
Akkermansia muciniphila Formulations Lyophilisation Storage Survival
Pedagogical Context
Citation
Freitas, A.; Almeida, D.; Machado, D.; Mendo, S.; Gomes, A. (2018) Formulation strategies for enhancing growth of akkermansia muciniphila and its survival through lyophilisation and storage at air ambient, In Book of Abstracts of the 12th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health. June 18th – 21st 2018, Budapest, Hungary