Browsing by Issue Date, starting with "2023-10-01"
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- Psychological violence within a partner relationship and alcohol abuse of Portuguese women: the mediating role of resiliencePublication . Fernandes, Bárbara; Dias, Paulo C.; Lopes, SílviaIn this study, we explored how psychological violence within a partner relationship relates to resilience and alcohol abuse of Portuguese women, particularly, testing the mediating role of resilience. A cross-sectional sample of 464 Portuguese women with a partner relationship was screened for psychological violence, alcohol abuse, and resilience. Results showed differences in terms of age, marital status, and current employment situation. Psychological violence was negatively related to resilience and positively related to alcohol consumption. Resilience also showed a negative relationship with alcohol consumption. A partial mediation was found between psychological violence and alcohol consumption through resilience, supporting the crucial role of resilience to break the negative “chain” between psychological violence and alcohol consumption.
- Oral manifestations of COVID-19 and its management in pediatric patients: a systematic review and practical guidelinePublication . Nasiri, Kamyar; Tehrani, Sahar; Mohammadikhah, Meysam; Banakar, Morteza; Alaeddini, Mojgan; Etemad-Moghadam, Shahroo; Fernandes, Gustavo V. O.; Heboyan, Artak; Imannezhad, Shima; Abbasi, FaridObjectives: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus causes coronavirus disease 2019 (COVID-19), a respiratory infection that has spread worldwide and is responsible for a high death toll. Although respiratory symptoms are the most common, there is growing evidence that oral signs of COVID-19 can also be seen in children. The purpose of this systematic review is to provide a comprehensive analysis of the available data on the oral manifestations of COVID-19 in children and to recommend appropriate methods of diagnosis and treatment. Methods: A systematic search of the MEDLINE, EMBASE, Scopus, and Web of Science databases was done to discover relevant papers published between their establishment and January 2023. Articles detailing oral symptoms in pediatric patients with confirmed COVID-19 infection were included, and data on clinical characteristics, diagnosis, treatment, and outcomes were extracted and evaluated. Results: A total of 24 studies involving 2112 pediatric patients with COVID-19 were included in the review. The most common presentations are oral lesions, taste and smell disorders, oral candidiasis, hemorrhagic crust, tongue discoloration, lip and tongue fissuring, gingivitis, and salivary gland inflammation. These manifestations were sometimes associated with multi-system inflammatory syndrome in children (MIS-C) or Kawasaki disease (KD). Management strategies varied depending on the severity of the oral manifestation and ranged from symptomatic relief with topical analgesics to systemic medications. Conclusion: Oral symptoms of COVID-19 are relatively prevalent in juvenile patients and can be accompanied by severe systemic diseases, such as MIS-C or Kawasaki illness. Early detection and adequate care of these oral symptoms are critical for the best patient results. Understanding the underlying pathophysiology and developing targeted treatments requires more investigation.
- Who gains and who loses from more information in technology markets? Evidence from the Sunshine ActPublication . Zhang, Huiyan; Branstetter, Lee; Conti, Raffaele; Mamadehussene, SamirResearch Summary: We consider the context of a technology market where participants (in particular, sellers) differ in reputation, and sellers observed participating in the transactions might suffer a reputation loss. Our theoretical model predicts that low-reputation idea sellers, thanks to the improvement in information disclosure, are more likely to be involved in technology transactions; at the same time, high-reputation idea sellers, to protect their reputations, might prefer avoiding any transactions. This shift in seller composition might affect the quantity and quality of collaborations. To test our theory, we assess the effect of the Physician Payment Sunshine Act on physician-firm collaborations. Overall, our findings indicate that while information disclosure might benefit some market participants, it can have unintended negative consequences for others. Managerial Summary: In technology markets, more information about market participants generally leads to better outcomes. However, in contexts where sellers suffer a reputation loss if their transactions become known, higher-reputation sellers may leave the market, affecting the quality of ideas being traded and impacting buyers. On the other hand, lower-reputation sellers may benefit from increased visibility and share their ideas more frequently. Our research examined these effects in the context of the Physician Payment Sunshine Act, which made physician collaborations with medical device companies visible. The results suggest that the effects of information disclosure are not uniform and that some market participants may benefit while others may suffer losses.
- Locations of objects are better remembered than their identities in naturalistic scenes: an eye-tracking experiment in mild cognitive impairmentPublication . Coco, Moreno I.; Maruta, Carolina; Martins, Isabel Pavão; Sala, Sergio DellaObjective: Retaining the identity or location of decontextualized objects in visual short-term working memory (VWM) is impaired by healthy and pathological ageing, but research remains inconclusive on whether these two features are equally impacted by it. Moreover, it is unclear whether similar impairments would manifest in naturalistic visual contexts. Method: 30 people with mild cognitive impairment (MCI) and 32 age-matched control participants (CPs) were eye-tracked within a change detection paradigm. They viewed 120 naturalistic scenes, and after a retention interval (1 s) asked whether a critical object in the scene had (or not) changed on either: identity (became a different object), location (same object but changed location), or both (changed in location and identity). Results: MCIs performed worse than CP but there was no interaction with the type of change. Changes in both were easiest while changes in identity alone were hardest. The latency to first fixation and first-pass duration to the critical object during successful recognition was not different between MCIs and CPs. Objects that changed in both features took longer to be fixated for the first time but required a shorter first pass compared to changes in identity alone which displayed the opposite pattern. Conclusions: Locations of objects are better remembered than their identities; memory for changes is best when involving both features. These mechanisms are spared by pathological ageing as indicated by the similarity between groups besides trivial differences in overall performance. These findings demonstrate that VWM mechanisms in the context of naturalistic scene information are preserved in people with MCI.
- Descobrir o Minho com Maria Ondina BragaPublication . Mateus, Isabel Cristina Brito Pinto; Martins, José Cândido de Oliveira
- Pricing of project finance bonds: a comparative analysis of primary market spreadsPublication . Guedes, Sebastião S.; Pinto, João M.This paper provides a comparative analysis of project finance (PF) and traditional corporate finance (CF) bond spreads and pricing. Using a cross-section of 47,196 bonds issued worldwide in the 1993–2020 period, we show that PF and CF bonds are differently priced, PF bonds have higher spreads than comparable CF bonds, and although ratings are the most important pricing determinant for PF and CF bonds at issuance, investors rely on other contractual, macroeconomic, and firms' characteristics beyond these ratings. Our results do not support the hypothesis of PF transactions as mechanisms of reducing sponsoring firms' funding costs: the cost of borrowing affects financing choices and PF transactions' weighted average spread is higher than that of comparable CF bond deals. We also find that economies of scale, risk management, and information asymmetry arguments affect sponsoring firms' choice between PF and CF transactions.
- Phytochemical screening, nutritional value, antioxidant and antimicrobial activities and acute toxicity of Scolymus hispanicus: a wild edible plant in MoroccoPublication . Aboukhalaf, Abdelghani; Moujabbir, Sara; El Amraoui, Belkassem; Kalili, Adil; Essaih, Seloua; Rocha, João Miguel; Belahsen, RekiaScolymus hispanicus L. (Golden thistle) is a well-known wild edible plant (WEP) in Morocco. However, the species value is not well investigated and its economic value is considerably low. Therefore, the aim of this work was to evaluate the phytochemical composition, the biological activities, and the acute toxicity of crude extract of S. hispanicus aerial parts. The mineral composition was assessed using an ICP-AES spectrometer and, the contents in polyphenol, flavonoids and tannins using colorimetric methods. The antioxidant activity was tested by DPPH assay. Disc diffusion and broth micro dilution methods were used to evaluate the antimicrobial activity. Moreover, the safety of the plant extract was validated by performing acute toxicity. The findings revealed that this plant is a rich source of protein, carbohydrates and minerals especially iron and, have high contents of polyphenols, flavonoids and tannins. The biological evaluation of the plant extracts exhibited a remarkable antioxidant content and, a wide antibacterial activity and yeast inhibition. The results indicated also that the tested extract is safe with an LD50 higher than 5000 mg.kg-1. The study data suggest that S. hispanicus could be a promising functional and nutraceutical food with antioxidant and antimicrobial potential and can contribute to a balanced diet.
- Relation of gender to atherosclerotic plaque characteristics by differing angiographic stenosis severityPublication . Jonas, Rebecca; Patel, Toral; Crabtree, Tami R.; Jennings, Robert S.; Heo, Ran; Park, Hyung Bok; Marques, Hugo; Chang, Hyuk Jae; Stuijfzand, Wijnand J.; van Rosendael, Alexander R.; Choi, Jung Hyun; Doh, Joon Hyung; Her, Ae Young; Koo, Bon Kwon; Nam, Chang Wook; Shin, Sang Hoon; Cole, Jason; Gimelli, Alessia; Khan, Muhammad Akram; Lu, Bin; Gao, Yang; Nabi, Faisal; Al-Mallah, Mouaz H.; Nakazato, Ryo; Schoepf, U. Joseph; Driessen, Roel S.; Bom, Michiel J.; Thompson, Randall C.; Jang, James J.; Ridner, Michael; Rowan, Chris; Avelar, Erick; Généreux, Philippe; Knaapen, Paul; de Waard, Guus A.; Pontone, Gianluca; Andreini, Daniele; Bax, Jeroen J.; Choi, Andrew D.; Earls, James P.; Hoffmann, Udo; Min, James K.; Villines, Todd C.It is unknown whether gender influences the atherosclerotic plaque characteristics (APCs) of lesions of varying angiographic stenosis severity. This study evaluated the imaging data of 303 symptomatic patients from the derivation arm of the CREDENCE (Computed TomogRaphic Evaluation of Atherosclerotic Determinants of Myocardial IsChEmia) trial, all of whom underwent coronary computed tomographic angiography and clinically indicated nonemergent invasive coronary angiography upon study enrollment. Index tests were interpreted by 2 blinded core laboratories, one of which performed quantitative coronary computed tomographic angiography using an artificial intelligence application to characterize and quantify APCs, including percent atheroma volume (PAV), low-density noncalcified plaque (LD-NCP), noncalcified plaque (NCP), calcified plaque (CP), lesion length, positive arterial remodeling, and high-risk plaque (a combination of LD-NCP and positive remodeling ≥1.10); the other classified lesions as obstructive (≥50% diameter stenosis) or nonobstructive (<50% diameter stenosis) based on quantitative invasive coronary angiography. The relation between APCs and angiographic stenosis was further examined by gender. The mean age of the study cohort was 64.4 ± 10.2 years (29.0% female). In patients with obstructive disease, men had more LD-NCP PAV (0.5 ± 0.4 vs 0.3 ± 0.8, p = 0.03) and women had more CP PAV (11.7 ± 1.6 vs 8.0 ± 0.8, p = 0.04). Obstructive lesions had more NCP PAV compared with their nonobstructive lesions in both genders, however, obstructive lesions in women also demonstrated greater LD-NCP PAV (0.4 ± 0.5 vs 1.0 ± 1.8, p = 0.03), and CP PAV (17.4 ± 16.5 vs 25.9 ± 18.7, p = 0.03) than nonobstructive lesions. Comparing the composition of obstructive lesions by gender, women had more CP PAV (26.3 ± 3.4 vs 15.8 ± 1.5, p = 0.005) whereas men had more NCP PAV (33.0 ± 1.6 vs 26.7 ± 2.5, p = 0.04). Men had more LD-NCP PAV in nonobstructive lesions compared with women (1.2 ± 0.2 vs 0.6 ± 0.2, p = 0.02). In conclusion, there are gender-specific differences in plaque composition based on stenosis severity.