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Browsing by Issue Date, starting with "2008-11"

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  • Futurologia no passado - possibilidades entre o homem e o computador
    Publication . Sá, Cristina; Cortez, Nuno
    A futurologia no passado fala do agora vivido pelas gerações vindouras. Fazer futurologia é falar do presente no espaço de amanhã, um espaço-tempo que não se desagrega, tal como a distância não invalida a existência de dois locais. Falar do futuro é falar do sentido que o presente tem, é falar da potência e possibilidade que a actualidade encerra em si. Com este propósito em mente, discorrer-se-á sobre os potenciais cenários que vários autores, em diversas épocas, viram desenhar-se no futuro do seu presente. Todos eles foram reais à luz do seu contexto. Tomámos a evolução do computador - e a consequente alteração da sua relação com o homem – como modelo para pensar o presente numa ideia de futuro.
    2008-11Conference object Open access Show more
  • Impact of forced-aging process on madeira wine flavor
    Publication . Silva, Hugo Oliveira e; Pinho, Paula Guedes de; Machado, Beatriz P.; Hogg, Tim; Marques, J. C.; Câmara, José S.; Albuquerque, F.; Ferreira, António C. Silva
    The aim of this study was to determine the optimal temperature and baking time to obtain a Madeira wine considered typical by an expert panel. For this purpose simultaneous descriptive analyses of typical Madeira wines were performed, and seven descriptors were selected: “dried fruit”, “nutty”, “musty”, “baked”, “oak”, “mushroom”, and “brown sugar”. Up to 10 odor-active zones were the most frequently cited by the members of the GC-olfactometry panel as corresponding to the panel’s descriptors. The odor importance of each of the zones reported by the GC-O analysis was ranked by AEDA. Three odor zones were identified as common to both Malvasia and Sercial wines and had retention indices (RI) of 1993 (“brown sugar” and “toasted”), 2151 (“brown sugar”), and 2174 (“nutty”, “dried fruits”); sotolon was identified as responsible for this last aroma. Several molecules were selected to be quantified on baked wines on the basis of AEDA results and expected Maillard volatiles, such as sotolon, furfural, 5-methylfurfural, 5-ethoximethylfurfural, methional, and phenylacetaldehyde. It was observed that typicity scores were positively correlated with the concentrations of sotolon and sugar and baking time and negatively with the fermentation length
    2008-11Journal article Restricted access Show more
  • Changes in red blood cells membrane protein composition during hemodialysis procedure
    Publication . Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Castro, Elisabeth; Miranda, Vasco; Faria, Maria do Sameiro; Loureio, Alfredo; Quintanilha, Alexandre; Belo, Luís; Santos-Silva, Alice
    Our aim was to evaluate the influence of the hemodialysis (HD) procedure in red blood cells (RBC) membrane protein composition. We evaluated hematological data (RBC count, hemoglobin concentration, and hematimetric indices) and RBC membrane protein composition (linear and exponential gradient polyacrylamide gel electrophoresis in the presence of sodium dodecylsulfate [SDS-PAGE] followed by densitometry analysis of RBC membrane proteins) before and immediately after the HD procedure in 20 patients (10 responders and 10 non-responders to recombinant human erythropoietin therapy [rhEPO]) and 26 healthy controls. Before HD, patients presented anaemia and significant changes in membrane protein composition, namely, a statistically significant reduction in spectrin associated with a significant increase in bands 6, as well as an altered membrane protein interaction (protein 4.1/spectrin, protein 4.1/band 3, protein 4.2/band 3 and spectrin/band 3). After HD, we found that patients showed a statistically significant increase in RBC count and hemoglobin, a further and statistically significant decrease in spectrin, an increase in band 3, and an altered spectrin/band 3 ratio. When comparing responders and non-responders patients after HD, we found that the non-responders presented a trend to a higher reduction in spectrin. Our data suggest that HD procedure seems to contribute to a reduction in spectrin, which is normally associated with a reduction in RBC deformability, being that reduction in spectrin is higher in non-responder patients.
    2008-11Journal article Open access Show more