Browsing by Author "Viegas, Carlos"
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- Biodentine for furcation perforation repair: an animal study with histological, radiographic and micro-computed tomographic assessmentPublication . Cardoso, Miguel; Pires, Maria dos Anjos; Correlo, Vitor; Reis, Rui; Paulo, Manuel; Viegas, CarlosIntroduction: Biodentine has been scarcely studied as a furcation perforation (FP) repair material, mostly by in vitro methodologies. This animal study aimed to compare the histological responses, radiographic, and micro-computed tomographic (micro-CT) outcomes after FP repair with Biodentine or ProRoot MTA (MTA) in dogs’ teeth. Methods and Materials: Fifty teeth from five dogs were divided into 4 groups: MTA (n=20, FP repaired with ProRoot MTA), BDT (n=20, FP repaired with Biodentine), PC (n=5, positive control, FP without repair) and NC (n=5, negative control, without perforation). The animals were euthanized after 4 months. Histological assessment included inflammatory cell infiltration, hard tissue resorption, hard tissue repair, and cement repair in the furcation area. Immediate postoperative and 4 months follow-up radiographs were compared for radiolucency in the furcation region. The volume of extruded material was quantified using micro-CT images. Results: The tested materials showed equivalent radiographic response, together with similar hard tissue resorption and repair but, BDT group showed significantly less inflammation, lower volume of extruded material and higher cement repair than MTA group. Conclusion: The outcomes of this study, taken together with other favorable results in literature, are highly suggestive that Biodentine is a promising biomaterial to be used for FP repair.
- P7 - Evaluation of extruded material in furcation perforation repair with micro-computed tomographyPublication . Cardoso, Miguel; Noites, Rita; Correlo, Vitor; Viegas, CarlosBackground Furcation perforations are pathological conditions of complex treatment and, currently, bioceramics are good options for furcation perforations repair. The aim of this study was to compare the volume of extruded material with micro-computed tomographic (microCT) after Furcation Perforation (FP) repair with Biodentine (BDT) or ProRoot MTA (prMTA) in dogs’ teeth. Materials and methods Forty dogs’ teeth were divided into 2 groups: prMTA (n=20, FP repaired with ProRoot MTA), BDT (n=20, FP repaired with Biodentine). All animal procedures were approved by the institutional Ethical Committee and conformed with the ethical guidelines and regulations of the national Directorate-General for Food and Veterinary (Process number 0421/000/000/2014). The animals were euthanized after 4 months. The volume of extruded material was quantifed using microCT images. Statistical analysis was performed using independent-samples t-test in SPSS™. All diferences were considered signifcant at P≤0.05. Results Total volume of extruded material was signifcantly lower in BDT group than in prMTA group (BDT: 1.42±0.80mm3; prMTA: 2.27±1.67mm3; P=0.049). In both test material groups, microCT showed continuity between the extruded repair material and the surrounding bone. Along with the study’s included outcomes, further evaluation of microCT images allowed the identifcation of new mineralized tissue bridges over the remaining radicular pulp tissue in specimens of both test groups. Conclusions The greater amount of extruded material found for prMTA group is consistent with its lengthier setting time, which may contribute to the unintended compaction of the unset material into the furcation defect. Even though Biodentine presented lesser extrusion, a concomitant histologic study revealed similar results concerning mineralized tissue formation.