Percorrer por autor "Vaz, Josiana"
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- Exploring clinical trials to manage firefighters’ sleep quality: a PRISMA compliant systematic reviewPublication . Alves, Sara; Vaz, Josiana; Fernandes, AdíliaSleep research has grown over the past decades and investigators are deeply involved in studying sleep and its impact on human health and body regulation. Despite the understanding that insufficient sleep is strongly linked to the development of several disorders, unsatisfactory sleep exposes health and safety to innumerous risks. The present study aims to review and analyze the main results of clinical trials, registered at ClinicalTrials.gov and ICTRT databases, and developed construct strategies to improve sleep quality on firefighters and enhance professionals’ sleep and health conditions. The protocol was registered in PROSPERO under number CRD42022334719. Trials registered between first registry and 2022 were included. We retrieved 11 registered clinical trials; seven met eligibility criteria and were included in the review. A relation between sleep disorders, shift work, and occupational health problems was found, and retrieved trials showed that sleep education programs can improve sleep quality and sleep hygiene. Science has already recognized sleep’s importance for metabolic functioning and survivorship. Nevertheless, it continues to play a major role in discovering methods to diminish the problems faced. Strategies contemplating sleep education, or intervention, should be presented to fire services to tackle this problem and promote healthier and safer environments.
- Response surface methodology applied to essential oil extraction of eucalyptus leavesPublication . Hached, Hanine; Pedrosa, Mariana C.; Heleno, Sandrina; Barros, Lillian; Vaz, Josiana; Carocho, MarcioPlant volatiles are secondary metabolites with a wide range of applications in several industries, namely the textile, food, pharma, and perfumery. These molecules are usually from three major groups, the terpenoid, phenylpropanoid/benzenoid and fatty acid derivatives group. This work focused on applying the response surface methodology technique towards optimizing the yield in essential oils of Eucalyptus globulus Labill, extracted by hydro distillation. For this, three factors were varied, namely the time of extraction (variation between 180 to 270 min), particle size (varying between 1 and 3 mm), and solid/liquid ration (varying between 10 and 50 g/L). The response recorded was the amount (g) of recovered essential oil. Using the optimization function, the optimal points were set at 260 minutes of extraction time, particle size of 1.2 mm and 50 g/L ratio. The model was significant, and the lack of fit was not, allowing for an R2 of 0.9911 and an adjusted R2 of 0.9777. Figure 1 shows the 3D charts of the response-surface. The model predicted that, at the optimal point, the yield in essential oils is 0.707 g, an amount above the one found in any of the 17 extraction conditions performed. Overall, the most important of the three factors was the solid to liquid ratio, showing that this factor accounts for most variations in the amount of pure essential oil, followed by particle size and finally, the least important factor, extraction time. This study allows an optimization of the extraction of essential oils from eucalyptus by showing that larger amounts of extract render more oil, as well as smaller particle sizes, while the extraction time has a low influence, thus allowing for shorter extraction times, which corresponds to lower energetic waste. The results herein are important for the food industry, specifically for new food additives, but also as flavorings for grain-based foods.
