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Authors
Advisor(s)
Abstract(s)
Given the thermodynamic and kinetic limitations
which often constrain the extent of chemical reactions
and post-reactional separation processes, and
therefore constrain the yield and the degree of purity of
the resulting products, integration of reaction and separation
in a single unit has been under the scope of several
bioengineering researchers in recent years.
It is the aim of this work to compare the performance of
a cascade of N reactor/separator sets, either in series or in
parallel, with that of an integrated reaction/separation
unit. In order to do so, a Michaelis-Menten reaction in
dilute substrate solutions (i.e. a pseudo ®rst order reaction)
was considered to take place in either con®guration
and, under the same reaction and separation conditions,
comparison of the performance and ef®ciency of these
con®gurations was made in terms of fractional recovery of
pure product, total time required to achieve such recovery
and rate of recovery.
It was concluded that: (i) the series combination of
reactor/separator sets yields better results, both in terms of
fractional amount of product recovered and time required
to do so, than the parallel combination; and (ii) the integrated
approach is much more time- and cost-effective
than plain cascading, thus making it very attractive from
an economic point of view.
Description
Keywords
Pedagogical Context
Citation
PAIVA, A. L.; MALCATA, F. X. - reaction and separation relates to that of parallel and sequential configurations. Bioprocess Engineering. ISSN 0178-515X. Vol.22 (2000), p. 149-158
Publisher
Springer-Verlag