| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 2.84 MB | Adobe PDF |
Advisor(s)
Abstract(s)
The aim of this study was to infer about the modes and extent of dispersion of Sphingomonadaceae via tap
water. Sphingomonadaceae isolated from tap water samples in different places of a hospital were compared,
based on intra-species genetic variability and antibiotic resistance phenotypes. These isolates were also compared
with others isolated before from houses and dental chairs, served by the same municipal water supply
system. Sphingomonadaceae from hospital tap water comprised members of the genera Sphingomonas,
Sphingobium, Novosphingobium and Blastomonas. In general, distinct genotypes of Sphingomonadaceae were
detected in different hospital areas and in tap water outside the hospital, suggesting these bacteria are not
persistent or widespread in the urban water distribution system. Possible intrinsic antibiotic resistance,
observed in most or all members of the family or of a genus, was observed for colistin in Sphingomonadaceae,
aminoglycosides in the genus Blastomonas and beta-lactams in the genus Sphingobium. Possible acquired
resistance phenotypes, not common to all members of a given species, comprised fluoroquinolones, cephalosporins
and sulphonamides. Although the potential of Sphingomonadaceae as opportunistic pathogens may
be low, the capacity of these bacteria to thrive in water supply systems, combined with the intrinsic or
acquired antibiotic resistance, may raise the risk associated with their occurrence in hospital tap water.
Description
Keywords
Sphingomonadaceae Blastomonas Hospital Tap water Antibiotic resistance
Pedagogical Context
Citation
NARCISO-DA-ROCHA, Carlos; VAZ-MOREIRA Ivone; MANAIA, C.M. - Genotypic diversity and antibiotic resistance in Sphingomonadaceae isolated from hospital tap water. ISSN 0048-9697. Science of the Total Environment. Vol. 466–467 (2014), p. 127–135
Publisher
Elsevier