Publication
Wound-healing potentiation in mice treated with phenolic extracts of Moringa oleifera leaves planted at different climatic areas
| dc.contributor.author | Benkiran, Sara | |
| dc.contributor.author | Zinedine, Abdellah | |
| dc.contributor.author | Aziz, Tariq | |
| dc.contributor.author | Rocha, João Miguel | |
| dc.contributor.author | Ayam, Iman Msegued | |
| dc.contributor.author | Raoui, Sidi Mohammed | |
| dc.contributor.author | Chabir, Rachida | |
| dc.contributor.author | Errachidi, Faouzi | |
| dc.contributor.author | Alharbi, Metab | |
| dc.contributor.author | Albekairi, Thamer H. | |
| dc.contributor.author | Alasmari, Abdullah F. | |
| dc.date.accessioned | 2024-02-16T17:30:10Z | |
| dc.date.available | 2024-02-16T17:30:10Z | |
| dc.date.issued | 2024-01-03 | |
| dc.description.abstract | For years, Moringa oleifera has been known for possessing wound-healing properties. This study aimed to investigate the effect of two extracts: aqueous extract (AE) and ethanolic extract (EE) of Moringa oleifera leaves planted at two regions (Mssisi and Lamta) in Morocco for their anti-inflammatory and healing properties, for which mice were used as a biological model. Inflammation was monitored by assessing forepaw volume of mice, measured at 0 min, 1 h, 3 h, and 5 h, after its induction by carrageenan. Hind paw of mice were treated with extracts of M. oleifera, at a dose of 50 mg/kg, obtained from Mssisi region. This resulted in reduction of edema by 99.2% with EE and by 91.8% with AE, compared to controls and the phenolic extract of M. oleifera planted at Lamta region. Regarding healing of burns induced on rat’s dorsal region; results showed that application of Moringa-based ointment for 14 days, at a dose of 50 mg/kg on wounds, resulted in total healing, compared to controls (negative control: more than 22 days, and positive control: 22 days). M. oleifera extracts resulted in nearly complete tissue repair of 98.26% and 95.34% with EE and AE, respectively. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.doi | 10.15586/ijfs.v36i1.2454 | pt_PT |
| dc.identifier.eid | 85184145062 | |
| dc.identifier.issn | 1120-1770 | |
| dc.identifier.uri | http://hdl.handle.net/10400.14/44008 | |
| dc.identifier.wos | 001143886600002 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | pt_PT |
| dc.subject | Moringa oleifera | pt_PT |
| dc.subject | Aqueous extract | pt_PT |
| dc.subject | Ethanolic extract | pt_PT |
| dc.subject | Mice | pt_PT |
| dc.subject | Phenolic compounds | pt_PT |
| dc.subject | Wound-healing potentiation | pt_PT |
| dc.title | Wound-healing potentiation in mice treated with phenolic extracts of Moringa oleifera leaves planted at different climatic areas | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 43 | pt_PT |
| oaire.citation.issue | 1 | pt_PT |
| oaire.citation.startPage | 28 | pt_PT |
| oaire.citation.title | Italian Journal of Food Science | pt_PT |
| oaire.citation.volume | 36 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |