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Case report of clinical salmonellosis by salmonella typhimurium that occurred in portuguese children

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dc.contributor.authorFreixo, R.
dc.contributor.authorAlbano, H.
dc.contributor.authorSilva, J.
dc.contributor.authorTeixeira, P.
dc.date.accessioned2012-01-18T17:28:11Z
dc.date.available2012-01-18T17:28:11Z
dc.date.issued2011
dc.description.abstractAims: Aim of this study is to characterize clinical isolates of Salmonella Typhimurium that occurred in Portuguese children on the basis of their virulence and antimicrobial resistance profiles and pulsed-field gel electrophoresis typing and to analyse possible strain relatedness. Methods and Results: Different Salmonella serotypes were isolated from clinical cases of salmonellosis that had occurred in two Portuguese hospitals (a total of 259 isolates). All Salm. Typhimurium strains, with the age of the patients known, (total of 26 isolates) were selected for this study. These isolates were characterized for their virulence gene profiles (agfA, iroB, slyA, hin/H2, spv), antimicrobial resistance profiles and investigated for the occurrence of multi-drug-resistant Salm. Typhimurium DT 104 by PCR. Salmonella isolates showed high rates of resistance to four or more antibiotics, 100% resistance to sulfadiazine and a high percentage of strains with the resistance profile of Salm. Typhimurium DT 104, two of them with this phage type (determined by PCR). A relationship between some clusters and their resistance and virulence profiles was detected, each cluster having the same profile. Conclusions: This study showed high-antibiotic resistance of the Salmonella strains investigated, and the presence of multidrug-resistant Salm. Typhimurium DT104 in infections of Portuguese children. Significance and Impact of the Study: Study is based on regarding the increase in antibiotic resistance by Salmonella strains isolated from infections in Portuguese children and on the presence of Salm. Typhimurium DT 104 circulating in Portugal.por
dc.description.versioninfo:eu-repo/semantics/submittedVersion
dc.identifier.citationFREIXO, R....[et al] - Case report of clinical salmonellosis by Salmonella Typhimurium that occurred in Portuguese children. Letters in Applied Microbiology. ISSN 0266-8254. Vol. 53 n.º 3 (2011), p. 300-305por
dc.identifier.doi10.1111/j.1472-765X.2011.03106.x
dc.identifier.eissn1472-765X
dc.identifier.issn0266-8254
dc.identifier.urihttp://hdl.handle.net/10400.14/7508
dc.identifier.wosWOS:000293914800008
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherWileypor
dc.subjectAntimicrobial resistancepor
dc.subjectChildrenpor
dc.subjectPulsed-fieldpor
dc.subjectSalmonella Typhimuriumpor
dc.titleCase report of clinical salmonellosis by salmonella typhimurium that occurred in portuguese childrenpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage305
oaire.citation.issue3
oaire.citation.startPage300
oaire.citation.titleLetters in Applied Microbiology
oaire.citation.volume53
person.familyNameFreixo
person.familyNameAlbano
person.familyNameSilva
person.familyNameTeixeira
person.givenNameRicardo
person.givenNameHelena
person.givenNameJoana
person.givenNamePaula
person.identifier.ciencia-id0B18-052A-0C21
person.identifier.ciencia-id201A-0D1F-C0FC
person.identifier.ciencia-idB415-743D-D9F9
person.identifier.orcid0000-0002-3663-6604
person.identifier.orcid0000-0002-2798-1924
person.identifier.orcid0000-0003-3977-7418
person.identifier.orcid0000-0002-6296-5137
person.identifier.ridK-3400-2014
person.identifier.ridJ-8678-2014
person.identifier.scopus-author-id37080431500
person.identifier.scopus-author-id6602934854
person.identifier.scopus-author-id7403023130
person.identifier.scopus-author-id7005895206
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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