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Phenolic compounds modulation in β-farnesene fed-batch fermentation using sugarcane syrup as feedstock

dc.contributor.authorCarvalho, Luís Carlos
dc.contributor.authorOliveira, Ana L. S.
dc.contributor.authorCarsanba, Erdem
dc.contributor.authorPintado, Manuela
dc.contributor.authorOliveira, Carla
dc.date.accessioned2022-10-24T15:31:16Z
dc.date.available2024-09-30T00:30:58Z
dc.date.issued2022-11-15
dc.description.abstractSugarcane syrup is the feedstock used in the industrial production of β-farnesene through Saccharomyces cerevisiae fermentation. However, it contains phenolic compounds, which may interfere with yeast performance. The aim of this work was to modulate the transfer of phenolic compounds from sugarcane syrup to the broth, throughout 13 days of β-farnesene fed-batch fermentation in 2-L bioreactors. This was accomplished by applying two mathematical calculations: a mass balance and the Weibull kinetic model. The concentrations of most phenolic compounds increased until day 3 of fermentation and then remained constant until the end of the process. However, quantities of hydroxybenzaldehyde, protocatechuic, caffeic, ferulic and p-coumaric acids, decreased after day 2. The Weibull model exhibited better fit to the data, with an R2 of 0.85 or higher. This work provides for the first time a model describing phenolic accumulation in β-farnesene fermentation, which can be a valuable tool to apply in similar processes.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.doi10.1016/j.indcrop.2022.115721pt_PT
dc.identifier.eid85139049523
dc.identifier.issn0926-6690
dc.identifier.urihttp://hdl.handle.net/10400.14/39165
dc.identifier.wos000910922600011
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectFed-batch fermentationpt_PT
dc.subjectPhenolic compoundspt_PT
dc.subjectSaccharomyces cerevisiaept_PT
dc.subjectSugarcane syruppt_PT
dc.subjectβ-farnesenept_PT
dc.titlePhenolic compounds modulation in β-farnesene fed-batch fermentation using sugarcane syrup as feedstockpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleIndustrial Crops and Productspt_PT
oaire.citation.volume188pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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