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Study of the effects of chitosan upon Streptococcus mutans adherence and biofilm formation

2013Journal article Restricted access
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dc.contributor.authorCosta, E. M.
dc.contributor.authorSilva, S.
dc.contributor.authorTavaria, F. K.
dc.contributor.authorPintado, M. M.
dc.date.accessioned2014-05-08T10:44:35Z
dc.date.available2014-05-08T10:44:35Z
dc.date.issued2013
dc.description.abstractThe main aim of this work was to access the potential use of high and low molecular weight chitosans as potential oral antimicrobials, particularly as antibinfilm agents. Chitosan's interference with Streptococcus mutans capability to adhere and form biofilms was assessed. Additionally the effect upon mature and polymicrobial biofilms was also evaluated. The results obtained showed that chitosan was capable of interfering with S. mutans adhesion and primary biofilm formation. This action was observed up to a week with little to none decrease in efficiency. In addition chitosan was capable of inhibiting biofilms formed by two microorganisms and was capable of acting upon mature biofilms leading to significant reductions (94%) in biofilm survival. However clear statistical differences (p < 0.05) were registered in all assays with, in most assays, HMw chitosan presenting higher efficiency than LMw chitosan. Considering this results chitosan's potential as a valid alternative to traditional antimicrobials in oral health it's evident.por
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationCOSTA, E.M....[et al.] - Study of the effects of chitosan upon Streptococcus mutans adherence and biofilm formation. Anaerobe. ISSN 1075-9964. Vol. 20 (2013), p. 27-31por
dc.identifier.doi10.1016/j.anaerobe.2013.02.002
dc.identifier.eissn1095-8274
dc.identifier.issn1075-9964
dc.identifier.urihttp://hdl.handle.net/10400.14/14288
dc.identifier.wosWOS:000317709700005
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relationQREN-ADI 3474
dc.relationStrategic Project - LA 16 - 2011-2012
dc.subjectStreptococcus mutanspor
dc.subjectAdherencepor
dc.subjectBiofilmpor
dc.subjectMature biofilmpor
dc.subjectChitosanpor
dc.subjectSub-MICpor
dc.titleStudy of the effects of chitosan upon Streptococcus mutans adherence and biofilm formationpor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - LA 16 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0016%2F2011/PT
oaire.citation.endPage31
oaire.citation.startPage27
oaire.citation.titleAnaerobe
oaire.citation.volume20
oaire.fundingStream6817 - DCRRNI ID
person.familyNameCosta
person.familyNameSilva
person.familyNameKekhasharú Tavaria
person.familyNamePintado
person.givenNameEduardo
person.givenNameSara
person.givenNameFreni
person.givenNameMaria Manuela
person.identifier1888852
person.identifier456608
person.identifier.ciencia-idB218-870B-98B5
person.identifier.ciencia-id8E18-0AFF-BF6D
person.identifier.ciencia-id1B15-5DAD-7B27
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0003-3121-4514
person.identifier.orcid0000-0001-8268-2137
person.identifier.orcid0000-0002-6273-6668
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id55249865700
person.identifier.scopus-author-id55158300800
person.identifier.scopus-author-id6602645613
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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