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The influence of diet and obesity in Lynch syndrome: what do we know so far

dc.contributor.authorRodrigues, Cláudio
dc.contributor.authorIrving, Susana Couto
dc.contributor.authorAlves, Paula
dc.contributor.authorDinis-Ribeiro, Mário
dc.contributor.authorBrandão, Catarina
dc.contributor.authorCorreia, Marta
dc.date.accessioned2025-01-10T16:49:28Z
dc.date.available2025-01-10T16:49:28Z
dc.date.issued2024-12-17
dc.description.abstractOf all new cases of colorectal cancer, Lynch syndrome (LS) accounts for approximately 3%. This syndrome is the most common hereditary cancer syndrome and is caused by pathogenic variants in the genes responsible for DNA mismatch repair. Although the relationship between colorectal cancer risk and diet is well established, little is known regarding the influence of diet and nutritional characteristics on LS’s clinical evolution. There is some evidence suggesting that individuals living with LS should follow general guidelines for diet and alcohol restriction/moderation, so as to achieve and maintain a favorable weight status and overall health and quality of life. However, more research is needed, preferentially from clinical studies of a prospective nature with robust designs, to better inform diet and behavioral patterns targeting cancer prevention in LS.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/nu16244352pt_PT
dc.identifier.eid85213412217
dc.identifier.issn2072-6643
dc.identifier.pmcPMC11677193
dc.identifier.pmid39770972
dc.identifier.urihttp://hdl.handle.net/10400.14/47746
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBody fatpt_PT
dc.subjectBody mass indexpt_PT
dc.subjectColorectal cancer riskpt_PT
dc.subjectDietpt_PT
dc.subjectLynch syndromept_PT
dc.titleThe influence of diet and obesity in Lynch syndrome: what do we know so farpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue24pt_PT
oaire.citation.titleNutrientspt_PT
oaire.citation.volume16pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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