Publicação
White spot lesions: diagnosis and treatment – a systematic review
| dc.contributor.author | Lopes, Pedro C. | |
| dc.contributor.author | Carvalho, Teresa | |
| dc.contributor.author | Gomes, Ana T. P. C. | |
| dc.contributor.author | Veiga, Nélio | |
| dc.contributor.author | Blanco, Leticia | |
| dc.contributor.author | Correia, Maria | |
| dc.contributor.author | Mello-Moura, Anna Carolina Volpi | |
| dc.date.accessioned | 2026-07-13T15:18:56Z | |
| dc.date.available | 2026-07-13T15:18:56Z | |
| dc.date.issued | 2023-08-11 | |
| dc.description.abstract | Background: Dental caries is one of the most prevalent pathologies in the world and its first stage appears as a white spot lesion. It is important to know its activity and the differential diagnoses. There are several ways to diagnose an injury and several clinical approaches to its treatment. The aim of this study is related to a previously established PICO(S) question: “Do new diagnostic tools have the potential to change the conventional treatment of white spots?”. Methods: A systematic search of available studies in the literature was carried out in Pubmed and Scopus electronic databases and manually to identify relevant articles. This systematic review included trials complying the following inclusion criteria: (1) being in humans, (2) being in English, (3) being about white spot lesions, (4) have been published between 2012 and 2023, (5) having both diagnosis and treatment and (6) having full text available. In this review we excluded other systematic reviews of clinical trials and studies in vitro. The RoB tool was used to assess the risk of bias. Results: The systematic literature search identified 143 potentially relevant references, which after applying the exclusion criteria, resulted in only 22 articles. Regarding diagnostic methods, most articles found were based on visual examination (10) or fluorescence (7). The least referenced diagnostic techniques were based on the use of clinical photographs (2), cross-sectional microrafiography (1) and computed microtomography (1). The use of DIAGNOdent was reported by 3 studies. With regard to therapies, most studies reported the use of infiltrating resin (7) and fluoride-based products (5). Other studies have reported the use of SAPP11-4 (1), home care (1), CPP-ACP (2) and HCL (1). Combination therapies were also considered: 2 studies reported the use of fluoride varnish, 2 studies used infiltrating resin and fluoride varnish, and one study reported the use of a combination of fluoride varnish and chlorhexidine. | eng |
| dc.identifier.doi | 10.21203/rs.3.rs-3178070/v1 | |
| dc.identifier.other | e1c80c24-dc46-4538-bdd5-42e13713d7ec | |
| dc.identifier.uri | http://hdl.handle.net/10400.14/58713 | |
| dc.language.iso | eng | |
| dc.publisher | Research Square Platform LLC | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | White spot lesion | eng |
| dc.subject | Dental caries | eng |
| dc.subject | Diagnosis | eng |
| dc.subject | Treatment | eng |
| dc.title | White spot lesions: diagnosis and treatment – a systematic review | |
| dc.type | preprint | |
| dspace.entity.type | Publication | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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