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Orientador(es)
Resumo(s)
The balance equations pertaining to the modelling of a CSTR performing an enzyme-catalyzed reaction in the presence of enzyme deactivation are developed. Combination
of heuristic correlations for the size-dependent cost of equipment and the purification-dependent cost of recovery of
product with the mass balances was used as a basis for the development of expressions relating a (suitably defined) dimensionless economic parameter with the optimal outlet
substrate concentration under the assumption that overall production costs per unit mass of product were to be minimized. The situation of Michaelis Menten kinetics for the substrate depletion and first order kinetics for the deactivation of enzyme (considering that the free enzyme and the enzyme in the enzyme/substrate complex deactivate at different rates) was
explored, and plots for several values of the parameters germane to the analysis are included.
Descrição
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Contexto Educativo
Citação
MALCATA, F. X. - Cost minimization in the predesign of an enzymatic CSTR: an overall approach. Bioprocess Engineering. ISSN 0178-515X. Vol. 13 (1995), p. 51-55
Editora
Springer