Repository logo
 
Publication

Effects of processing and storage on Pediococcus pentosaceus SB83 in vaginal formulations: lyophilized powder and tablets

2013Journal article Open access
Simple item page
dc.contributor.authorBorges, Sandra
dc.contributor.authorCosta, Paulo
dc.contributor.authorSilva, Joana
dc.contributor.authorTeixeira, Paula
dc.date.accessioned2014-05-08T15:11:53Z
dc.date.available2014-05-08T15:11:53Z
dc.date.issued2013
dc.description.abstractVaginal probiotics have an important role in preventing the colonization of the vagina by pathogens. This study aimed to investigate different formulations with Pediococcus pentosaceus SB83 (lyophilized powder and tablets with and without retarding polymer) in order to verify its stability and antilisterial activity after manufacture and during storage. The bacteriocinogenic activity of P. pentosaceus SB83 against Listeria monocytogenes was evaluated in simulated vaginal fluid. Suspension of Pediococcus pentosaceus SB83 reduced the pathogen only after 2 h and the lyophilized bacteria after 24 h of contact, and, in the tablets, P. pentosaceus SB83 lost the antimicrobial activity. The pH of simulated vaginal fluid decreased for all the tested conditions. As lyophilized powder demonstrated better results concerning antimicrobial activity, this formulation was selected to evaluate the antilisterial activity during the 12 months of storage. During storage at room temperature, lyophilized bacteria totally inhibited the pathogen only until one month of storage. At 4 degrees C, P. pentosaceus SB83 showed antimicrobial activity during all the time of storage investigated. Therefore, the better formulation of P. pentosaceus SB83 is the lyophilized powder stored at 4 degrees C, which may be administered intravaginally as a washing solution.
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationBORGES, Sandra...[et al.] - Effects of Processing and Storage on Pediococcus pentosaceus SB83 in Vaginal Formulations: Lyophilized Powder and Tablets. BioMed Research International. ISSN 2314-6133. Vol. 2013 (2013), 8 p.por
dc.identifier.doi10.1155/2013/680767
dc.identifier.eissn2314-6141
dc.identifier.issn2314-6133
dc.identifier.urihttp://hdl.handle.net/10400.14/14339
dc.identifier.wosWOS:000321350100001
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherHindawipor
dc.relationStrategic Project - LA 16 - 2011-2012
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleEffects of processing and storage on Pediococcus pentosaceus SB83 in vaginal formulations: lyophilized powder and tabletspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - LA 16 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0016%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F45496%2F2008/PT
oaire.citation.issue680767
oaire.citation.titleBioMed Research International
oaire.citation.volume2013
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamSFRH
person.familyNameBorges
person.familyNameCardoso da Costa
person.familyNameSilva
person.familyNameTeixeira
person.givenNameSandra
person.givenNamePaulo Jorge
person.givenNameJoana
person.givenNamePaula
person.identifier.ciencia-id591F-66D5-8F90
person.identifier.ciencia-idF917-0147-AA0C
person.identifier.ciencia-idB415-743D-D9F9
person.identifier.orcid0000-0003-4665-1098
person.identifier.orcid0000-0002-1152-3398
person.identifier.orcid0000-0003-3977-7418
person.identifier.orcid0000-0002-6296-5137
person.identifier.ridG-2820-2011
person.identifier.ridJ-8678-2014
person.identifier.scopus-author-id15826021600
person.identifier.scopus-author-id7201895686
person.identifier.scopus-author-id7403023130
person.identifier.scopus-author-id7005895206
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication1b85edbf-9619-4aa7-affc-d8a47c7bb0ec
relation.isAuthorOfPublication6fcf2dd5-8529-4b63-98b4-37250694ab30
relation.isAuthorOfPublication42069f79-2050-47f2-a42b-fab5c301e9a3
relation.isAuthorOfPublicationb918d4a2-b9f9-4c56-8318-111625e4d58b
relation.isAuthorOfPublication.latestForDiscoveryb918d4a2-b9f9-4c56-8318-111625e4d58b
relation.isProjectOfPublication649dc879-e68a-45df-bcc4-1e66a0521a49
relation.isProjectOfPublication2dd4e579-05ec-4df5-aa1e-cab01c458a66
relation.isProjectOfPublication.latestForDiscovery2dd4e579-05ec-4df5-aa1e-cab01c458a66

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Borges_2013_Effects of Processing and Storage on Pediococcus pentosaceus SB83.pdf
Size:
1.15 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.44 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CBQF - Contribuições em Revistas Científicas / Contribution to Journals