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Advisor(s)
Abstract(s)
Three new sesquiterpene lactones (acetyltrifloculoside, 8,15-acetylsalonitenolide and 8-acetylsalonitenolide) and two known sesquiterpene lactones were isolated from a dichloromethane extract of the Portuguese liverwort Targionia lorbeeriana. Their structures were established by spectroscopic methods (EI and D/CI mass spectroscopy, 1H and 13C NMR) and that of acetyltrifloculoside was confirmed by X-ray crystallography. The three isolated guaianolide sesquiterpene lactones presented antifungal activity against Cladosporium cucumerinum and larvicidal activity against Aedes aegypti. Only one of the isolated lactones presented activity against Candida albicans.
Description
Keywords
Liverwort T. lorbeeriana Targionaceae Phytochemistry Bioassay Terpenoids Sesquiterpene lactones
Pedagogical Context
Citation
NEVES, Marta... [et al.] - New sesquiterpene lactones from the Portuguese liverwort Targionia lorbeeriana. Phytochemistry. ISSN 0031-9422. Vol. 49, n.º 6 (1999), p. 967-972
Publisher
Elsevier