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Re-emergence of yellow fever virus in Brazil: evidence from forest and peri-urban settings

2025-04-12Preprint Acesso aberto
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dc.contributor.authorAndrade, Valnete das Graças Dantas
dc.contributor.authorAdelino, Talita Emile Ribeiro
dc.contributor.authorFonseca, Vagner
dc.contributor.authorMelo Farias Moreno, Keldenn
dc.contributor.authorTomé, Luiz Marcelo Ribeiro
dc.contributor.authorPereira, Luiz Augusto
dc.contributor.authorLaRoque, Debora Glenda Lima de
dc.contributor.authorFilippis, Ana Maria Bispo de
dc.contributor.authorGarkauskas Ramos, Daniel
dc.contributor.authorRamalho, Dario Brock
dc.contributor.authorde Lima Furtado, Kátia Cristina
dc.contributor.authorBorges, Gleissy Adriane Lima
dc.contributor.authorMartins, Livia Caricio
dc.contributor.authorFrutuoso, Lívia C. V.
dc.contributor.authorOliveira Lamounier, Ludmila
dc.contributor.authorGuimarães, Natália Rocha
dc.contributor.authorBarros, Patrícia Miriam Sayuri Sato
dc.contributor.authorAlmeida, Priscila Souza de
dc.contributor.authorSilva, Paulo Eduardo de Souza da
dc.contributor.authorPinheiro, Rodrigo Giesbrecht
dc.contributor.authorStabeli, Rodrigo Guerino
dc.contributor.authorChagas, Shirley Moreira da Silva
dc.contributor.authorPedroso, Sílvia Helena Sousa Pietra
dc.contributor.authorKashima, Simone
dc.contributor.authorPenante, Solange Gonçalves
dc.contributor.authorOliveira, Marília Santini de
dc.contributor.authorSilva, Vinicius Lemes da
dc.contributor.authorVoorhis, Wesley C. Van
dc.contributor.authorHolmes, Edward C.
dc.contributor.authorLourenço, José
dc.contributor.authorIani, Felipe Campos de Melo
dc.contributor.authorJúnior, Alberto Simões Jorge
dc.contributor.authorGiovanetti, Marta
dc.contributor.authorAlcantara, Luiz Carlos Junior
dc.date.accessioned2026-08-03T15:25:45Z
dc.date.available2026-08-03T15:25:45Z
dc.date.issued2025-04-12
dc.description.abstractYellow Fever virus (YFV) continues to challenge public health systems across the Americas, despite decades of successful control and the availability of a highly effective vaccine. Following major outbreaks between 2016 and 2022, YFV re-emerged in Brazil in 2023, with a confirmed infection in a non-human primate in São Paulo linked to viral strains circulating in the Midwest region. This reintroduction, combined with increased YFV activity reported across the Americas, signals an ongoing risk of viral persistence and geographic expansion. In this study, we investigate recent YFV dynamics in forest and peri-urban settings, integrating genomic evidence with ecological and spatial data to trace transmission pathways and assess the potential for urban re-emergence. Our findings highlight the need for sustained surveillance in both sylvatic and transitional zones, especially amid fluctuating vaccine coverage and environmental changes that may facilitate spillover events.eng
dc.identifier.doi10.1101/2025.04.10.25325467
dc.identifier.other366ff296-9268-4a1d-a383-9ef37777a5c0
dc.identifier.urihttp://hdl.handle.net/10400.14/59008
dc.language.isoeng
dc.publishermedRxiv
dc.rights.urihttp://creativecommons.org/licenses/by-nd/4.0/
dc.subjectYellow fever virus (YFV)eng
dc.subjectBrazileng
dc.subjectSylvatic transmissioneng
dc.subjectRe-emergenceeng
dc.subjectGenomic surveillanceeng
dc.titleRe-emergence of yellow fever virus in Brazil: evidence from forest and peri-urban settings
dc.typepreprint
dspace.entity.typePublication
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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