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Drug delivery systems for vaginal infections

dc.contributor.authorBorges, Sandra
dc.contributor.authorBarbosa, Joana
dc.contributor.authorTeixeira, Paula
dc.date.accessioned2017-10-12T11:40:18Z
dc.date.available2017-10-12T11:40:18Z
dc.date.issued2016
dc.description.abstractVaginal infections are one of the most common gynecological problems. The lower female genital tract can be infected by various pathogens such as virus (human immunodeficiency virus, HIV), bacteria (Gardnerella vaginalis), fungi (Candida spp.) or parasites (Trichomonas vaginalis). The vagina has been the local for the delivery of therapeutic agents. Depending on the antimicrobial agents, different dosage forms have been developed, comprising douches, creams, ointments, gels, foams, tablets, ovules, rings, tampons and, more recently, vaginal films. Innovative approaches, like encapsulation technologies, have emerged in an attempt to overcome the several limitations of the existing systems for vaginal administration of therapeutic agents. This review explores the antimicrobial agents that can be used for vaginal infections therapy, the various vaginal dosage forms to deliver these therapeutic agents, their advantages and limitations and the novel advances in the area of vaginal drug delivery.
dc.description.versioninfo:eu-repo/semantics/proofpt_PT
dc.identifier.citationBORGES, Sandra; BARBOSA; Joana; TEIXEIRA, Paula - Drug Delivery Systems for Vaginal Infections. In ATTA-UR-RAHMAN (ed.) - Frontiers in clinical drug research: anti-infectives. Sharjah: Bentham Science Publishers, 2016. E-ISBN 978-1-68108-153-3. Vol. 2, chap 3, p. 233-258pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.14/23020
dc.language.isoengpt_PT
dc.peerreviewednopt_PT
dc.titleDrug delivery systems for vaginal infectionspt_PT
dc.typebook part
dspace.entity.typePublication
oaire.citation.titleFrontiers in clinical drug research (anti-infectives)pt_PT
person.familyNameBorges
person.familyNameBarbosa
person.familyNameTeixeira
person.givenNameSandra
person.givenNameJoana
person.givenNamePaula
person.identifier.ciencia-id591F-66D5-8F90
person.identifier.ciencia-id9516-589F-8B0D
person.identifier.orcid0000-0003-4665-1098
person.identifier.orcid0000-0001-5879-9458
person.identifier.orcid0000-0002-6296-5137
person.identifier.ridJ-8678-2014
person.identifier.scopus-author-id15826021600
person.identifier.scopus-author-id13608752600
person.identifier.scopus-author-id7005895206
rcaap.rightsrestrictedAccesspt_PT
rcaap.typebookPartpt_PT
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relation.isAuthorOfPublicationce89919c-98a7-473c-995a-1d89e70644b6
relation.isAuthorOfPublicationb918d4a2-b9f9-4c56-8318-111625e4d58b
relation.isAuthorOfPublication.latestForDiscoveryb918d4a2-b9f9-4c56-8318-111625e4d58b

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