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The influence of metabolic profile of obese men on the severity of erectile dysfunction: are metabolically healthy obese individuals protected?

dc.contributor.authorMoura, Adriana
dc.contributor.authorTomada, Inês
dc.contributor.authorTomada, Nuno
dc.date.accessioned2018-09-20T12:04:54Z
dc.date.available2018-09-20T12:04:54Z
dc.date.issued2018
dc.description.abstractObjective: To determine the prevalence of erectile dysfunction (ED) in metabolically healthy obese (MHO) individuals, and to compare ED severity and hypogonadism prevalence in MHO, metabolically unhealthy obese (MUO) and metabolically healthy non-obese individuals. Material and methods: ED patients (n=460) were evaluated by standardized protocol, that included clinical evaluation, abridged 5-item version of the International Index of Erectile Function (IIEF-5) questionnaire survey, and Penile Duplex Doppler Ultrasound (PDDU) exam. Patients were classified as obese [body mass index (BMI) ≥30.0 kg/m2] and non-obese (BMI <30.0 kg/m2), and metabolic health status was defined by National Cholesterol Education Program Adult Treatment Panel III (NCEP ATPIII) criteria. Statistical analysis was performed and statistical significance was considered at p-level <0.05. Results: The mean age of the subjects was 56.2±10.5 years. MHO was present in 40% of obese individuals (n=37). MUO had lower mPSV compared to MHO (28.1 cm/s vs. 36.9 cm/s; p=0.005), and IIEF-5 scores were also lower in MUO compared to MHO patients (10.2 vs. 13.1; p=0.018). No statistical differences in IIEF-5 score, mPSV and hypogonadism prevalence between MHO and metabolically healthy non-obese (MHNO) patients were observed. Conclusion: Our results lead us to conclude that healthy metabolic profile protects obese individuals from severity of ED. The strong association between obesity and ED may be otherwise attributed to metabolic abnormalities present in the obese.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.citationMoura, A., Tomada, I., Tomada, N. (2018). The influence of metabolic profile of obese men on the severity of erectile dysfunction: are metabolically healthy obese individuals protected?. Turkish Journal Urolology, 44(6), 455-461pt_PT
dc.identifier.doi10.5152/tud.2018.66281pt_PT
dc.identifier.eid85057139962
dc.identifier.eissn2149-3057
dc.identifier.issn2149-3235
dc.identifier.pmid30201077
dc.identifier.urihttp://hdl.handle.net/10400.14/25721
dc.identifier.wos000446900000003
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTurkish Association of Urology
dc.titleThe influence of metabolic profile of obese men on the severity of erectile dysfunction: are metabolically healthy obese individuals protected?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage461
oaire.citation.issue6
oaire.citation.startPage455
oaire.citation.titleTurkish Journal Urolologypt_PT
oaire.citation.volume44
person.familyNameMoura
person.familyNameTomada
person.familyNameTomada
person.givenNameAdriana
person.givenNameInês
person.givenNameNuno
person.identifier2689332
person.identifier2227202
person.identifier.ciencia-id7719-7A32-37A7
person.identifier.ciencia-id5B1B-6BB9-4655
person.identifier.orcid0000-0002-9991-6320
person.identifier.orcid0000-0003-4660-0645
person.identifier.orcid0000-0002-9379-6030
person.identifier.scopus-author-id25223994400
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication7800d8c9-811c-4626-a25d-63bf79ba41f0
relation.isAuthorOfPublication18f09a66-7909-4d3e-90ac-82b21040cd31
relation.isAuthorOfPublication9bf81be1-c7db-40d1-be04-f79d9c337a30
relation.isAuthorOfPublication.latestForDiscovery9bf81be1-c7db-40d1-be04-f79d9c337a30

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