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Genomics-based timely detection of dengue virus type I genotypes I and V in Uruguay

2024-11-30Journal article Open access
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dc.contributor.authorMorel, Noelia
dc.contributor.authorGiovanetti, Marta
dc.contributor.authorFonseca, Vagner
dc.contributor.authorBurgueño, Analía
dc.contributor.authorLima, Mauricio
dc.contributor.authorCastro, Emerson
dc.contributor.authorGuimarães, Natália R.
dc.contributor.authorIani, Felipe C. M.
dc.contributor.authorBormida, Victoria
dc.contributor.authorCortinas, Maria Noel
dc.contributor.authorRamas, Viviana
dc.contributor.authorCoppola, Leticia
dc.contributor.authorBento, Ana I.
dc.contributor.authorRosewell, Alexander
dc.contributor.authorFranco, Leticia
dc.contributor.authorRico, Jairo Mendez
dc.contributor.authorLourenço, José
dc.contributor.authorAlcantara, Luiz Carlos Junior
dc.contributor.authorChiparelli, Hector
dc.date.accessioned2024-11-20T13:23:32Z
dc.date.available2024-11-20T13:23:32Z
dc.date.issued2024-11-30
dc.description.abstractThis study details a genomics-based approach for the early detection of mosquito-borne pathogens, marked by Uruguay's first ever complete genomic sequencing of Dengue Virus type I genotypes I and V. This pioneering effort has facilitated the prompt identification of these genotypes within the country, enabling Uruguayan public health authorities to develop timely and effective response strategies. Further integrated into this approach is a climate-driven suitability measure, closely associated with Dengue case reports and indicative of the local climate's role in the virus's transmission in the country within the changing climate context. The detection of multiple DENV-1 genotypes co-circulating in Uruguay underscores the necessity for proactive surveillance, particularly at borders, to prevent the introduction and dissemination of novel viral strains within the country and the region. This approach aids in facilitating prompt public health responses and intervention strategies, which are crucial in mitigating the impact of dengue outbreaks.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.heliyon.2024.e39246pt_PT
dc.identifier.eid85208454734
dc.identifier.issn2405-8440
dc.identifier.urihttp://hdl.handle.net/10400.14/47243
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectDengue viruspt_PT
dc.subjectGenomic monitoringpt_PT
dc.subjectSouth Americapt_PT
dc.subjectUruguaypt_PT
dc.titleGenomics-based timely detection of dengue virus type I genotypes I and V in Uruguaypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue22pt_PT
oaire.citation.titleHeliyonpt_PT
oaire.citation.volume10pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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