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Bioactive lipids in Dunaliella salina: implications for functional foods and health

dc.contributor.authorPais, Rita
dc.contributor.authorConde, Tiago
dc.contributor.authorNeves, Bruna B.
dc.contributor.authorPinho, Marisa
dc.contributor.authorCoelho, Marta
dc.contributor.authorPereira, Hugo
dc.contributor.authorRodrigues, Alexandre M. C.
dc.contributor.authorDomingues, Pedro
dc.contributor.authorGomes, Ana Maria
dc.contributor.authorUrbatzka, Ralph
dc.contributor.authorDomingues, Rosário
dc.contributor.authorMelo, Tânia
dc.date.accessioned2024-11-06T16:54:09Z
dc.date.available2024-11-06T16:54:09Z
dc.date.issued2024-10-19
dc.description.abstractDunaliella salina is a green microalga extensively explored for β-carotene production, while knowledge of its lipid composition is still limited and poorly investigated. Among lipids, polar lipids have been highlighted as bioactive phytochemicals with health-promoting properties. This research aimed to provide an in-depth lipidome profiling of D. salina using liquid and gas chromatography coupled with mass spectrometry. The lipid content was 6.8%, including phospholipids, glycolipids, betaine lipids, sphingolipids, triglycerides, diglycerides, and pigments. Among the total esterified fatty acids, 13.6% were 18:3 omega-3 and 14.7% were 18:1 omega-9. The lipid extract of D. salina showed anti-inflammatory activity by inhibiting cyclooxygenase-2 activity at 100 µg/mL, dose-dependent antioxidant scavenging activity, and antidiabetic activity by inhibiting α-glucosidase activity at 25 and 125 µg/mL. In conclusion, the lipid extract of D. salina has the potential to be used as a functional food ingredient or in the nutraceutical and cosmeceutical industries.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/foods13203321pt_PT
dc.identifier.eid85207677974
dc.identifier.issn2304-8158
dc.identifier.pmcPMC11507028
dc.identifier.pmid39456383
dc.identifier.urihttp://hdl.handle.net/10400.14/47140
dc.identifier.wos001341653000001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectFatty acidspt_PT
dc.subjectFoodpt_PT
dc.subjectLipidomicspt_PT
dc.subjectLipidspt_PT
dc.subjectMicroalgaept_PT
dc.titleBioactive lipids in Dunaliella salina: implications for functional foods and healthpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue20pt_PT
oaire.citation.titleFoodspt_PT
oaire.citation.volume13pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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