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A novel direct contact method for the assessment of the antimicrobial activity of dental cements

2013Journal article Restricted access
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dc.contributor.authorCosta, E. M.
dc.contributor.authorSilva, S.
dc.contributor.authorMadureira, A. R.
dc.contributor.authorCardelle-Cobas, A.
dc.contributor.authorTavaria, F. K.
dc.contributor.authorPintado, M. M.
dc.date.accessioned2014-05-08T10:47:53Z
dc.date.available2014-05-08T10:47:53Z
dc.date.issued2013
dc.description.abstractDental cements are a crucial part of the odontological treatment, however, due to the hazardous nature and reduced biological efficiency of some of the used materials, newer and safer alternatives are needed, particularly so those possessing higher antimicrobial activity than their traditional counterparts. The evaluation of the antimicrobial properties of solid and semi-solid antimicrobials, such as dental cements and gels, is challenging, particularly due to the low sensitivity of the current methods. Thus, the main aim of this study was the evaluation of the antimicrobial activity of a novel chitosan containing dental cement while simultaneous assessing/validating a new, more efficient, method for the evaluation of the antimicrobial activity of solid and gel like materials. The results obtained showed that the proposed method exhibited a higher sensitivity than the standard 96 well microtiter assay and allowed the determination of bactericidal activity. Additionally, it is interesting to note that the chitosan containing cement, which presented higher antimicrobial activity than the traditional zinc oxide/eugenol mix, was capable of inducing a viable count reduction above 5 log of CFU for all of the studied microorganisms.por
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationCOSTA, E.M....[et al.] - A novel direct contact method for the assessment of the antimicrobial activity of dental cements. Journal of Microbiological Methods. ISSN 0167-7012. Vol. 93 (2013), p. 168–172por
dc.identifier.doi10.1016/j.mimet.2013.03.014
dc.identifier.eissn1872-8359
dc.identifier.issn0167-7012
dc.identifier.urihttp://hdl.handle.net/10400.14/14289
dc.identifier.wosWOS:000319646900002
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.relationStrategic Project - LA 16 - 2011-2012
dc.subjectAntimicrobialpor
dc.subjectChitosanpor
dc.subjectDental cementpor
dc.subjectNovel methodpor
dc.titleA novel direct contact method for the assessment of the antimicrobial activity of dental cementspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - LA 16 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0016%2F2011/PT
oaire.citation.endPage172
oaire.citation.issue3
oaire.citation.startPage168
oaire.citation.titleJournal of Microbiological Methods
oaire.citation.volume93
oaire.fundingStream6817 - DCRRNI ID
person.familyNameCosta
person.familyNameSilva
person.familyNameMadureira
person.familyNameCardelle Cobas
person.familyNameKekhasharú Tavaria
person.familyNamePintado
person.givenNameEduardo
person.givenNameSara
person.givenNameRaquel
person.givenNameAlejandra
person.givenNameFreni
person.givenNameMaria Manuela
person.identifier1888852
person.identifierM-4659-2013
person.identifier456608
person.identifier.ciencia-idB218-870B-98B5
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person.identifier.ciencia-id1B15-5DAD-7B27
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0003-3121-4514
person.identifier.orcid0000-0001-8268-2137
person.identifier.orcid0000-0001-6596-1927
person.identifier.orcid0000-0002-1271-513X
person.identifier.orcid0000-0002-6273-6668
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridM-4659-2013
person.identifier.ridK-7183-2017
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id55249865700
person.identifier.scopus-author-id55158300800
person.identifier.scopus-author-id8384097900
person.identifier.scopus-author-id9736687700
person.identifier.scopus-author-id6602645613
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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