Publication
Production of 1,3-Propanediol by Clostridium butyricum VPI 3266 in continuous cultures with high yield and productivity
| dc.contributor.author | González-Pajuelo, M. | |
| dc.contributor.author | Andrade, J. C. | |
| dc.contributor.author | Vasconcelos, I. | |
| dc.date.accessioned | 2011-10-22T08:58:59Z | |
| dc.date.available | 2011-10-22T08:58:59Z | |
| dc.date.issued | 2005-07 | |
| dc.description.abstract | The effects of dilution rate and substrate feed concentration on continuous glycerol fermentation by Clostridium butyricum VPI 3266, a natural 1,3-propanediol producer, were evaluated in this work. A high and constant 1,3-propanediol yield (around 0.65 mol/mol), close to the theoretical value, was obtained irrespective of substrate feed concentration or dilution rate. Improvement of 1,3-propanediol volumetric productivity was achieved by increasing the dilution rate, at a fixed feed substrate concentration of 30, 60 or 70 g l-1. Higher 1,3-propanediol final concentrations and volumetric productivities were also obtained when glycerol feed concentration was increased from 30 to 60 g l-1, at D=0.05–0.3 h-1, and from 60–70 g l-1, at D=0.05 and 0.1 h-1. 30 g l-1 of 1,3-propanediol and the highest reported value of productivity, 10.3 g l-1 h-1, was achieved at D=0.30 h-1 and 60 g l-1 of feed glycerol. A switch to an acetate/butyrate ratio higher than one was observed for 60 g l-1 of feed glycerol and a dilution rate higher than 0.10 h-1; moreover, at D=0.30 h-1 3-hydroxypropionaldehyde accumulation was observed for the first time in the fermentation broth of C. butyricum. | por |
| dc.identifier.citation | "Journal of Industrial Microbiology & Biotechnology" . ISSN 1367-5435. 32:9 (2005) 391-396 | por |
| dc.identifier.uri | http://hdl.handle.net/10400.14/6755 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Springer | por |
| dc.relation.publisherversion | The original publication is available at www.springerlink.com | por |
| dc.title | Production of 1,3-Propanediol by Clostridium butyricum VPI 3266 in continuous cultures with high yield and productivity | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| person.familyName | Andrade | |
| person.familyName | Vasconcelos | |
| person.givenName | José | |
| person.givenName | Isabel | |
| person.identifier | 684026 | |
| person.identifier.ciencia-id | 2D1D-00CA-016F | |
| person.identifier.ciencia-id | 851B-41B9-4746 | |
| person.identifier.orcid | 0000-0002-2403-6062 | |
| person.identifier.orcid | 0000-0002-0565-3516 | |
| person.identifier.rid | N-3870-2013 | |
| person.identifier.scopus-author-id | 55415967800 | |
| person.identifier.scopus-author-id | 7003767794 | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
| relation.isAuthorOfPublication | b5156d42-c49f-4991-8aa9-fc77cfff8a33 | |
| relation.isAuthorOfPublication | 251ce926-a408-483f-a3df-acebe6631477 | |
| relation.isAuthorOfPublication.latestForDiscovery | b5156d42-c49f-4991-8aa9-fc77cfff8a33 |
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