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Impact of a purified blueberry extract on in vitro probiotic mucin-adhesion and its effect on probiotic/intestinal pathogen systems

dc.contributor.authorSilva, Sara
dc.contributor.authorCosta, Eduardo M.
dc.contributor.authorOliveira, Hélder
dc.contributor.authorFreitas, Vitor de
dc.contributor.authorMorais, Rui M.
dc.contributor.authorCalhau, Conceição
dc.contributor.authorPintado, Manuela
dc.date.accessioned2022-10-24T16:42:22Z
dc.date.available2022-10-24T16:42:22Z
dc.date.issued2022-10-18
dc.description.abstractSeveral arguments have been made to substantiate the need for natural antimicrobials for the food industry. With blueberry extracts, the most compelling are both their healthy connotation and the possibility of obtaining a multipurpose solution that can be an antioxidant, colorant, and antimicrobial. From an antimicrobial perspective, as blueberry/anthocyanin-rich extracts have been associated with a capacity to inhibit harmful bacteria while causing little to no inhibition on potential probiotic microorganisms, the study of potential benefits that come from synergies between the extract and probiotics may be of particular interest. Therefore, the present work aimed to evaluate the effect of an anthocyanin-rich extract on the adhesion of five different probiotics as well as their effect on the probiotics’ capacity to compete with or block pathogen adhesion to a mucin/BSA-treated surface. The results showed that, despite some loss of probiotic adhesion, the combined presence of extract and probiotic is more effective in reducing the overall amount of adhered viable pathogen cells than the PROBIOTIC alone, regardless of the probiotic/pathogen system considered. Furthermore, in some instances, the combination of the extract with Bifidobacterium animalis Bo allowed for almost complete inhibition of pathogen adhesionpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/molecules27206991pt_PT
dc.identifier.eid85140891977
dc.identifier.issn1420-3049
dc.identifier.pmcPMC9611478
dc.identifier.pmid36296591
dc.identifier.urihttp://hdl.handle.net/10400.14/39167
dc.identifier.wos000873235900001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectProbioticpt_PT
dc.subjectPathogenpt_PT
dc.subjectAdhesionpt_PT
dc.titleImpact of a purified blueberry extract on in vitro probiotic mucin-adhesion and its effect on probiotic/intestinal pathogen systemspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue20pt_PT
oaire.citation.titleMoleculespt_PT
oaire.citation.volume27pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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