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Hesperidin from orange peel as a promising skincare bioactive: an overview

dc.contributor.authorRodrigues, Cristina V.
dc.contributor.authorPintado, Manuela
dc.date.accessioned2024-02-23T11:39:04Z
dc.date.available2024-02-23T11:39:04Z
dc.date.issued2024-02-04
dc.description.abstractThe pursuit for better skin health, driven by collective and individual perceptions, has led to the demand for sustainable skincare products. Environmental factors and lifestyle choices can accelerate skin aging, causing issues like inflammation, wrinkles, elasticity loss, hyperpigmentation, and dryness. The skincare industry is innovating to meet consumers’ requests for cleaner and natural options. Simultaneously, environmental issues concerning waste generation have been leading to sustainable strategies based on the circular economy. A noteworthy solution consists of citrus by-product valorization, as such by-products can be used as a source of bioactive molecules. Citrus processing, particularly, generates substantial waste amounts (around 50% of the whole fruit), causing unprecedented environmental burdens. Hesperidin, a flavonoid abundant in orange peels, is considered to hold immense potential for clean skin health product applications due to its antioxidant, anti-inflammatory, and anticarcinogenic properties. This review explores hesperidin extraction and purification methodologies as well as key skincare application areas: (i) antiaging and skin barrier enhancement, (ii) UV radiation-induced damage, (iii) hyperpigmentation and depigmentation conditions, (iv) wound healing, and (v) skin cancer and other cutaneous diseases. This work’s novelty lies in the comprehensive coverage of hesperidin’s promising skincare applications while also demonstrating its potential as a sustainable ingredient from a circular economy approach.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/ijms25031890pt_PT
dc.identifier.eid85184696553
dc.identifier.issn1661-6596
dc.identifier.pmid38339165
dc.identifier.urihttp://hdl.handle.net/10400.14/44076
dc.identifier.wos001160296600001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectFood industry byproductspt_PT
dc.subjectHesperidinpt_PT
dc.subjectOrange peelspt_PT
dc.subjectRenewable bioactive compoundspt_PT
dc.subjectSustainable skincare formulationspt_PT
dc.titleHesperidin from orange peel as a promising skincare bioactive: an overviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue3pt_PT
oaire.citation.titleInternational Journal of Molecular Sciencespt_PT
oaire.citation.volume25pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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