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Application of a ventilator associated pneumonia prevention guideline and outcomes: a quasi-experimental study

dc.contributor.authorSousa, Ana Sabrina
dc.contributor.authorFerrito, Cândida
dc.contributor.authorPaiva, José Artur
dc.date.accessioned2018-11-15T16:29:53Z
dc.date.available2018-11-15T16:29:53Z
dc.date.issued2019
dc.description.abstractObjective: Ventilator associated pneumonia is the most frequent health-care-associated infection in Intensive Care Units, causing increased antibiotic consumption and resistance, length of stay, plus multiple health and economic costs. The aim of the study was to assess whether a customised guideline implementation would improve ventilator-associated pneumonia incidence and associated intensive care outcomes. Design: This was a quasi-experimental, before-after study consisting of pre-intervention, intervention and post-intervention periods. Setting: Three intensive care units at a well-known Portuguese hospital centre. Intervention: A set of eight recommendations was implemented after a guideline adaptation process. Patients: Adult patients admitted to the intensive care units over the study periods, aged 18 years or older and under invasive ventilation through an endotracheal tube or tracheostomy cannula. Measurements and main results: Data related to patient characterisation, guideline compliance and health outcomes were analysed. From a population of 1970 patients, a study sample of 828 was studied. Compliance with the recommendations was high. We identified a significant reduction in the incidence of ventilator-associated pneumonia in two of the units (p = 0.020 and p = 0.001) and a reduction in duration of invasive ventilation, intensive care unit length of stay and mortality in all the three units. We found associations between some recommendations and the implementation of the set of recommendations and intensive care unit length of stay, duration of invasive ventilation and mortality. Conclusion: The implementation of an evidence-based, locally customised guideline may improve ventilator associated pneumonia incidence and several outcomes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSousa, A. S., Ferrito, C., & Paiva, J. A. (2019). Application of a ventilator associated pneumonia prevention guideline and outcomes: A quasi-experimental study. Intensive and Critical Care Nursing, 51, 50–56. https://doi.org/10.1016/j.iccn.2018.10.001pt_PT
dc.identifier.doi10.1016/j.iccn.2018.10.001pt_PT
dc.identifier.eid85055129734
dc.identifier.eissn1532-4036
dc.identifier.issn0964-3397
dc.identifier.pmid30366645
dc.identifier.urihttp://hdl.handle.net/10400.14/26041
dc.identifier.wos000460338700008
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectCritical carept_PT
dc.subjectCross-infectionpt_PT
dc.subjectGuidelinept_PT
dc.subjectHealthcare costspt_PT
dc.subjectIntensive care unitpt_PT
dc.subjectIntubation associated pneumoniapt_PT
dc.subjectLength of staypt_PT
dc.subjectMortality ratept_PT
dc.subjectPreventionpt_PT
dc.subjectVentilator-associated pneumoniapt_PT
dc.titleApplication of a ventilator associated pneumonia prevention guideline and outcomes: a quasi-experimental studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage56
oaire.citation.startPage50
oaire.citation.titleIntensive and Critical Care Nursingpt_PT
oaire.citation.volume51
person.familyNameSousa
person.familyNameFerrito
person.givenNameAna Sabrina
person.givenNameCândida
person.identifier.ciencia-idEF1F-93B9-F49A
person.identifier.ciencia-idE81B-8BF4-68ED
person.identifier.orcid0000-0002-7694-2323
person.identifier.orcid0000-0002-2834-8573
person.identifier.scopus-author-id57195486137
person.identifier.scopus-author-id57195483256
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9605b46b-76fb-4ebf-ac39-4abbc72a59a3
relation.isAuthorOfPublication635d05bd-d33a-46fd-aa9f-6ae86cfe6473
relation.isAuthorOfPublication.latestForDiscovery9605b46b-76fb-4ebf-ac39-4abbc72a59a3

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