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A review on antifungal activity of mushroom (basidiomycetes) extracts and isolated compounds

2013Journal article Open access
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dc.contributor.authorAlves, Maria José
dc.contributor.authorFerreira, Isabel C. F. R.
dc.contributor.authorDias, Joana
dc.contributor.authorTeixeira, Vânia
dc.contributor.authorMartins, Anabela
dc.contributor.authorPintado, Manuela
dc.date.accessioned2013-10-03T15:49:52Z
dc.date.available2013-10-03T15:49:52Z
dc.date.issued2013
dc.description.abstractThe present review reports the antifungal activity of mushroom extracts and isolated compounds including high (e. g. peptides and proteins) and low (e. g. sesquiterpenes and other terpenes, steroids, organic acids, acylcyclopentenediones and quinolines) molecular weight compounds. Most of the studies available on literature focused on screening of antifungal activity of mushroom extracts, rather than of isolated compounds. Data indicate that mushroom extracts are mainly tested against different Candida species, while mushroom compounds are mostly tested upon other fungi. Therefore, the potential of these compounds might be more useful in food industry than in clinics. Oudemansiella canarii and Agaricus bisporus methanolic extracts proved to be the most active mushroom extracts against Candida spp. Grifolin, isolated from Albatrellus dispansus, seemed to be the most active compound against phytopathogenic fungi. Further studies should be performed in order to better understand the mechanism of action of this and other antifungal compounds as well as safety issues.por
dc.identifier.citationALVES, Maria José...[et al.] - A Review on Antifungal Activity of Mushroom (Basidiomycetes) Extracts and Isolated Compounds. Current Topics in Medicinal Chemistry.ISSN 1568-0266. Vol. 13, n.º 21 (2013), 2648-2659por
dc.identifier.doi10.2174/15680266113136660191
dc.identifier.eissn1873-5294
dc.identifier.issn1568-0266
dc.identifier.urihttp://hdl.handle.net/10400.14/12863
dc.identifier.wosWOS:000326986900002
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherBentham Science Publisherspor
dc.relationPortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
dc.relationStrategic Project - LA 16 - 2011-2012
dc.relationStrategic Project - UI 690 - 2011-2012
dc.subjectAntifungal activitypor
dc.subjectAntifungal proteinspor
dc.subjectBasidiomycetespor
dc.subjectGrifolinpor
dc.titleA review on antifungal activity of mushroom (basidiomycetes) extracts and isolated compoundspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitlePortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines
oaire.awardTitleStrategic Project - LA 16 - 2011-2012
oaire.awardTitleStrategic Project - UI 690 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FAGR-ALI%2F110062%2F2009/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0016%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FAGR%2FUI0690%2F2011/PT
oaire.citation.endPage2659
oaire.citation.issue21
oaire.citation.startPage2648
oaire.citation.volume13
oaire.fundingStream5876-PPCDTI
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameFerreira
person.familyNameMartins
person.familyNamePintado
person.givenNameIsabel
person.givenNameAnabela
person.givenNameMaria Manuela
person.identifier144781
person.identifier456608
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person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0003-4910-4882
person.identifier.orcid0000-0001-6218-4413
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridE-8500-2013
person.identifier.ridG-5488-2013
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id36868826600
person.identifier.scopus-author-id7203013518
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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