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- Shifting dynamics of Dengue virus serotype 2 and emergence of cosmopolitan genotype, Costa Rica, 2024Publication . González-Elizondo, Mauricio; Soto, Dihala Picado; Laurent, Estela Cordero; Martínez, Francisco Duarte; Alcantara, Luiz Carlos Junior; Fonseca, Vagner; Rico, Jairo Andrés Méndez; Lourenço, José; Franco, Leticia; Giovanetti, Marta; Garita, Claudio SotoDengue remains a major public health challenge. In Costa Rica, we implemented nationwide genomic surveillance to track dengue virus serotype 2 cosmopolitan genotype emergence. Phylogenetic and eco-epidemiologic analyses revealed early detection, climate-driven spread, and spatial heterogeneity. Our findings underscore the need for integrated surveillance to guide adaptive responses to emerging arboviral threats.