Browsing by Author "Reis, Filipa"
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- Cognitive impairment in prostate cancer patients receiving androgen deprivation therapy: a scoping reviewPublication . Barreira, João Vasco; Barreira, Pedro; Falcão, Gil; Garcez, Daniela; Silva, Pedro; Santos, Gustavo; Fontes-Sousa, Mário; Mendes, José Leão; Reis, Filipa; Santos, Carla F.; Ribeiro, Filipa; Capelas, Manuel LuísBackground: Androgen deprivation therapy (ADT) is a primary treatment for prostate cancer (PCa) that effectively reduces androgen levels to suppress tumor progression. However, growing evidence suggests potential cognitive side effects, raising concerns about the long-term neurological consequences of this treatment. Objective: This scoping review aims to synthesize the existing evidence linking ADT to cognitive changes in men with PCa, identifying the key cognitive domains affected and outlining gaps in the existing literature. Methods: A systematic literature search was conducted according to the PRISMA-ScR guidelines in CINAHL, PubMed, Scopus, and Web of Science. Studies investigating cognitive function in ADT-treated PCa patients were included, covering randomized controlled trials (RCTs) and cohort, case–control, and cross-sectional studies. The extracted data included the study design, evaluated cognitive characteristics, measurement tools, and overall findings. Results: A total of 22 studies met the inclusion and exclusion criteria. Cognitive assessments varied across studies. While some studies reported cognitive impairments in ADT-treated patients—particularly in working, verbal, and visual memory and executive function—others found no significant effects. The variability in prostate cancer staging, epidemiological study designs, and treatment regimens; the exclusion of comorbid conditions; and the differences in assessment tools, sample sizes, and study durations hinder definitive conclusions about the cognitive effects of ADT. Conclusions: This scoping review highlights the heterogeneous and often contradictory evidence regarding ADT-associated cognitive dysfunction. While certain cognitive domains may be affected, methodological inconsistencies limit robust conclusions. Standardized cognitive assessments and longer longitudinal studies are required to clarify ADT’s role in cognitive decline. As the PCa survival rate increases with extended ADT use, integrating routine cognitive monitoring into clinical practice should be considered for PCa patients.
- Controlling digital piracy via domain name system blocks: a natural experimentPublication . Reis, Filipa; Matos, Miguel Godinho de; Ferreira, PedroWe study the impact of batch DNS filtering of copyright-infringing websites, a novel administrative-based process that does not require judicial involvement. In partnership with a large telecommunication provider, we measure the impact of this intervention on piracy activity and the legal alternatives integrated into households' media subscription bundles, an aspect largely unexplored in prior literature. We find a significant reduction in Internet traffic, which proxies piracy activity. However, we do not observe statistically significant changes in the consumption of the legal alternatives under consideration, only a slight increase in TV viewership. To further understand these outcomes, we examine the heterogeneity of these results based on households' pre-block usage intensity of digital piracy and demographic characteristics. Our work contributes to the literature on the effectiveness of piracy control strategies and informs policy makers and industry practitioners about the benefits and limitations of DNS-based website blocking.
- The impact of time shifting on TV consumption and ad viewershipPublication . Belo, Rodrigo; Ferreira, Pedro; Matos, Miguel Godinho de; Reis, FilipaIn this paper we study the impact of time shifting on TV consumption and ad viewership. We analyze the results of a field experiment in which a random sample of “triple-play” households were given a set of premium TV channels broadcasting popular movies and TV shows without commercial breaks. A random subset of these households were given access to these channels with time shifting (automated cloud recording for later viewing or rewinding of broadcasted programs), while the remainder were not. This design allowed us to identify the effects of time shifting on TV consumption. On average, we found that receiving access to the channels with time shifting increased total TV consumption because it increased time-shifted viewership while leaving live viewership unchanged. The increase in the live viewership of these channels was similar to the reduction in the live viewership of the originally available channels, resulting in a net zero effect on live viewership. It appears that time shifting does not change the concentration of live viewership, but it does increase the concentration of total TV viewership, because it is used disproportionately to watch the most popular programs. Finally, we found that time shifting does not change the likelihood of skipping ads during live viewership, suggesting that households do not use time shifting to strategically avoid ads.