Santos, Inês C.Mesquita, RaquelRangel, António O. S. S.2016-01-212016-01-212015Santos, Inês C.; Mesquita, Raquel B.R.; Rangel, António O.S.S. - The State of the Art of Flow-Through Solid-Phase Spectrometry. LCGC - Chromatography online. (2015) 33(10), 1-7http://hdl.handle.net/10400.14/18974Sample pretreatment is one of the bottlenecks in analytical chemistry, especially when dealing with complex matrices like environmental samples. When performed in a batch mode, sample handling methods are tedious and time consuming. Therefore, the hyphenation of these methods with flow-injection techniques yields many advantages. The possibility of automation not only increases the determination rate, but also decreases sample and reagent consumption. As a consequence, analyte separation, enrichment, and elimination of sample matrix becomes possible with an increase in selectivity and sensitivity. This is a significant contribution for the analysis of environmental samples because the analyte is usually present at trace levels in a complex matrix. In this scenario, the state of the art of solid-phase spectrometry (SPS) with a focus on the lab-on-valve (LOV) platform is discussed. LOV facilitates the manipulation of bead suspension for SPS with lower reagents consumption and waste production.engjournal article2227-9075